Molecular genetics of chromosome 17 tauopathies

M Hutton - Annals of the New York Academy of Sciences, 2000 - Wiley Online Library
… Abstract: The identification of mutations in the gene encoding the micro-tubule associated
protein tau in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) …

Behavioural variant frontotemporal dementia—defining genetic and pathological subtypes

JD Rohrer - Journal of Molecular Neuroscience, 2011 - Springer
frontotemporal dementia (bvFTD) is the second most common young-onset neurodegenerative
dementia after … It forms part of the frontotemporal lobar degeneration (FTLD) spectrum of …

Genetics of dementia

CT Loy, PR Schofield, AM Turner, JBJ Kwok - The Lancet, 2014 - thelancet.com
genetic testing in dementia The first step in considering molecular genetic testing for dementia
… is helpful for families with a history of frontotemporal dementia. Estimation of age of onset …

Clinical, genetic and neuropathological features of frontotemporal dementia: an update and guide

JP Paulos, J Massano - Acta Médica Portuguesa, 2013 - actamedicaportuguesa.com
… Introduction: Frontotemporal Lobar Degeneration encompasses a group of … The genetic
underpinnings and histopathological aspects are quite diverse and form the basis of molecular

Alzheimer's disease and frontotemporal dementia: the current state of genetics and genetic testing since the advent of next-generation sequencing

JS Goldman, VM Van Deerlin - Molecular diagnosis & therapy, 2018 - Springer
… technology has changed genetic testing for Alzheimer’s disease (AD) and frontotemporal
dementia (FTD; also known as frontotemporal degeneration), two dementias that can overlap …

Genetic testing for amyotrophic lateral sclerosis and frontotemporal dementia: impact on clinical management

J Roggenbuck, JC Fong - Clinics in Laboratory Medicine, 2020 - labmed.theclinics.com
… Ten years ago, commercial genetic testing for amyotrophic lateral sclerosis (ALS) …
frontotemporal dementia (FTD). Recent years have brought rapid progress in the discovery of genes

Susceptible genes and disease mechanisms identified in frontotemporal dementia and frontotemporal dementia with Amyotrophic Lateral Sclerosis by DNA …

E Taskesen, A Mishra, S van der Sluis, R Ferrari… - Scientific reports, 2017 - nature.com
Molecular network analysis suggests a logical hypothesis for the pathological role of c9orf72
in amyotrophic lateral sclerosis/frontotemporal dementia. J Cent Nerv Syst Dis 6, 69–78, doi:…

The genetics of frontotemporal lobar degeneration

R Rademakers, M Hutton - Current neurology and neuroscience reports, 2007 - Springer
… As expected from the clinical and pathologic heterogeneity, the molecular genetics of FTLD
… and genetic findings of these families were compared and the term “frontotemporal dementia

Pick's disease and frontotemporal dementias: emerging clinical and molecular concepts

BL Miller, K Boone, D Geschwind… - The Neurologist, 1999 - journals.lww.com
… – Frontotemporal dementia (FTD) is a degenerative dementia that has increasingly captured
the interest of behavioral neurologists, neuropsychologists, and molecular … in molecular

Multifaceted genes in amyotrophic lateral sclerosis-frontotemporal dementia

R Ranganathan, S Haque, K Coley… - Frontiers in …, 2020 - frontiersin.org
genes and 3 FTD-associated genes (Table 1). This review will firstly summarize the genes
that have been recognized as ALS-FTD genes … and FTD causing genes where mutations have …