Fat Mass and Obesity Associated (FTO) Gene and Hepatic Glucose and Lipid Metabolism
TM Mizuno - Nutrients, 2018 - mdpi.com
… of whole-body FTO deficiency, while mice lacking FTO only … the metabolic phenotype
observed in mice with complete FTO deficiency [24,26]. A limited number of metabolic phenotypes (…
observed in mice with complete FTO deficiency [24,26]. A limited number of metabolic phenotypes (…
Association of a common rs9939609 variant in the fat mass and obesity-associated (FTO) gene with obesity and metabolic phenotypes in a Taiwanese population: a …
TJ Hsiao, E Lin - Journal of genetics, 2016 - Springer
… FTO gene has been the focus of attention in the obesity field. It has been reported that the FTO
… The A allele of the FTO rs9939609 SNP was identified to be associated with an increased …
… The A allele of the FTO rs9939609 SNP was identified to be associated with an increased …
The 'Fat Mass and Obesity Related' (FTO) gene: Mechanisms of Impact on Obesity and Energy Balance
JR Speakman - Current obesity reports, 2015 - Springer
… in the Ft segment was later cloned and named Fatso (Fto) [2], not because of any
phenotypic association to body fatness, but apparently because it was by far the largest …
phenotypic association to body fatness, but apparently because it was by far the largest …
FTO gene associated fatness in relation to body fat distribution and metabolic traits throughout a broad range of fatness
SII Kring, C Holst, E Zimmermann, T Jess, T Berentzen… - PloS one, 2008 - journals.plos.org
… For example, for the widely known association between obesity and blood … genetic variation
may be so small that we may overlook a true association with a related metabolic phenotype …
may be so small that we may overlook a true association with a related metabolic phenotype …
Association metabolic obesity phenotypes with cardiometabolic index, atherogenic index of plasma and novel anthropometric indices: a link of FTO-rs9939609 …
F Abolnezhadian, SA Hosseini, M Alipour… - Vascular Health and …, 2020 - Taylor & Francis
… obesity-risk allele AA of FTO gene were higher in obesity phenotypes than metabolic
phenotypes… significant difference of FTO-rs9939609 variant in obesity phenotypes. The genotype …
phenotypes… significant difference of FTO-rs9939609 variant in obesity phenotypes. The genotype …
The Fat Mass‐ and Obesity‐Associated (FTO) Gene to Obesity: Lessons from Mouse Models
JY Chang, JH Park, SE Park, J Shon, YJ Park - Obesity, 2018 - Wiley Online Library
… of genetic variants on obesity and other metabolic phenotypes are amplified or attenuated
by environmental factors, and the gene-environment interactions have been reported in FTO …
by environmental factors, and the gene-environment interactions have been reported in FTO …
Association between LEPR, FTO, MC4R, and PPARG-2 polymorphisms with obesity traits and metabolic phenotypes in school-aged children
SM Almeida, JM Furtado, P Mascarenhas, ME Ferraz… - Endocrine, 2018 - Springer
… to establish an association between clinical, metabolic phenotypes and LEPR rs11371101,
MC4R … parameters dependent from obesity and FTO rs9939609 in the same population. …
MC4R … parameters dependent from obesity and FTO rs9939609 in the same population. …
Obesity and FTO: changing focus at a complex locus
… in the larger deleted locus were responsible for the component parts of the diverse phenotypes
… scan shows genetic variants in the FTO gene are associated with obesity-related traits. …
… scan shows genetic variants in the FTO gene are associated with obesity-related traits. …
The FTO gene modifies weight, fat mass and insulin sensitivity in women with polycystic ovary syndrome, where its role may be larger than in other phenotypes
I Kowalska, MT Malecki, M Straczkowski, J Skupien… - … & metabolism, 2009 - Elsevier
… The data from the general population showed the effect of the FTO gene polymorphism on …
of the FTO gene variation on obesity, body fat, insulin sensitivity, and metabolic and hormonal …
of the FTO gene variation on obesity, body fat, insulin sensitivity, and metabolic and hormonal …
A Mouse Model for the Metabolic Effects of the Human Fat Mass and Obesity Associated FTO Gene
C Church, S Lee, EAL Bagg, JS McTaggart… - PLoS …, 2009 - journals.plos.org
… mouse Fto gene that results in a lean phenotype of reduced body weight and fat mass.
Physical activity and food intake is unchanged but metabolic rate is increased. We show by gene …
Physical activity and food intake is unchanged but metabolic rate is increased. We show by gene …
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