Bioinformatics tools and novel challenges in long non-coding RNAs (lncRNAs) functional analysis

L Da Sacco, A Baldassarre, A Masotti - International journal of molecular …, 2011 - mdpi.com
… Although next generation technologies in RNA sequencing (RNA-Seq) … lncRNAs putative
function that they assessed experimentally. This analysis revealed numerous sets of lncRNAs

[HTML][HTML] Discovery and functional analysis of lncRNAs: Methodologies to investigate an uncharacterized transcriptome

K Kashi, L Henderson, A Bonetti, P Carninci - Biochimica et Biophysica …, 2016 - Elsevier
sequencing technologies, have provided multiple approaches to detect and study lncRNAs.
… More precise technologies that study the interaction between lncRNA and chromatin will be …

Platforms for investigating LncRNA functions

JL Charles Richard… - SLAS TECHNOLOGY …, 2018 - journals.sagepub.com
sequencing technologies serving different applications. RNA sequencing and next-generation
sequencing technologies … A combination of computational and functional analysis such as …

Identification and Functional Analysis of LncRNAs in Response to Seed Aging in Metasequoia glyptostroboides by Third Generation Sequencing Technology

Y Luo, J Le, Y Zhang, R Wang, Q Li, X Lu, J Liu, Z Deng - Forests, 2022 - mdpi.com
… can provide ultralong reference sequences for RNA-Seq studies … study, we used the SMRT
sequencing technology of the PacBio platform to perform full-length transcriptome sequencing

Functional analysis of long noncoding RNAs in development and disease

LL Chen, JC Zhao - Systems Biology of RNA Binding Proteins, 2014 - Springer
… been made in discovery of novel lncRNAs following improvement in RNA sequencing (RNA-seq) …
in order to “fish out” associated proteins is a reliable way to analyze lncRNA function. …

RNA sequencing and functional analysis implicate the regulatory role of long non-coding RNAs in tomato fruit ripening

B Zhu, Y Yang, R Li, D Fu, L Wen… - … of experimental botany, 2015 - academic.oup.com
… in fruit ripening, it is necessary and urgent to discover and identify novel lncRNAs and
understand the function of lncRNAs in tomato fruit ripening. Here it is reported that 3679 …

The hitchhikers' guide to RNA sequencing and functional analysis

JW Chen, L Shrestha, G Green, A Leier… - Briefings in …, 2023 - academic.oup.com
… RNA sequencing technologies have revolutionized biology and biomedical sciences, sequencing
LncRNAs are profiled by sequencing transcriptomes using polyA-selected or stranded …

Technological developments in lncRNA biology

S Jathar, V Kumar, J Srivastava, V Tripathi - Long Non Coding RNA …, 2017 - Springer
… cell lines using four complementary sequencing technologies (deep sequencing, CAGE, …
function analysis. Several approaches have been adopted to effectively deplete target lncRNAs

Revealing lncRNA structures and interactions by sequencing-based approaches

X Qian, J Zhao, PY Yeung, QC Zhang… - Trends in biochemical …, 2019 - cell.com
functional roles of lncRNA in gene expression and RNA metabolism, as well as in development
and disease. In this review, we summarize the latest sequencing … map functional lncRNAs

Identification and functional analysis of long non-coding RNA (lncRNA) in response to seed aging in rice

Y Zhang, F Fan, Q Zhang, Y Luo, Q Liu, J Gao, J Liu… - Plants, 2022 - mdpi.com
… RNA sequencing of samples from rice embryos, analyzed the differences in expression of
rice seed lncRNAs … With the rapid development of high-throughput sequencing technology, …