Functional Characterisation of Highly Conserved and Structurally Prominent Residues of 2‐Methylisoborneol Synthase

B Gu, JS Dickschat - Chemistry–A European Journal, 2023 - Wiley Online Library
… the N-terminal proline-rich domain of unknown function appeared disordered. Here we report
on the functional characterisation of two MIBSs that are distantly related to the MIBSs from …

Identification and functional characterisation of genes and corresponding enzymes involved in carnitine metabolism of Proteus sp.

C Engemann, T Elssner, S Pfeifer, C Krumbholz… - Archives of …, 2005 - Springer
… However functional characterisation of the components of … coli, a function as a potential
transcriptional activator was … Furthermore, protein databases contained no characterised proteins

Structural and functional characterisation of staphylococcal superantigen-like protein 11 (SSL11)

MC Chung - 2008 - researchspace.auckland.ac.nz
… This thesis describes the investigation into the structure and function of the related protein,
SSL11. The binding specificity of SSL11 has been identified as the trisaccharide Neu5Acα2-…

Isolation, Cloning, and Characterisation of a trp Homologue from Squid (Loligo forbesi) Photoreceptor Membranes

PD Monk, A Carne, SH Liu, JW Ford… - Journal of …, 1996 - Wiley Online Library
… Degenerate oligonucleotides designed on the basis of the protein sequence data were
used to screen a size-fractionated squid retinal cDNA library using a PCR-based strategy. DNA …

[HTML][HTML] Unbiased screening of polymer libraries to define novel substrates for functional hepatocytes with inducible drug metabolism

DC Hay, S Pernagallo, JJ Diaz-Mochon, CN Medine… - Stem cell …, 2011 - Elsevier
… screened polymer libraries for novel and bioactive substrata. Following polymer library screening
… In order to study hepatic function in further detail the hit polymers were screened for the …

[HTML][HTML] A first generation inhibitor of human Greatwall kinase, enabled by structural and functional characterisation of a minimal kinase domain construct

CA Ocasio, MB Rajasekaran, S Walker, D Le Grand… - Oncotarget, 2016 - ncbi.nlm.nih.gov
… Two small-molecule compound libraries, enriched with pharmacophores known to interact
with the ATP-binding site of protein kinases, were screened as a pooled library in a Kinase-…

Characterisation of a putative M23-domain containing protein in Mycobacterium tuberculosis

AO Papadopoulos, C Ealand, BG Gordhan… - Plos one, 2021 - journals.plos.org
… Herein, we investigate the function of the Rv0950-encoded putative M23 endopeptidase
in M. … Herein, we describe the characterisation of an M23 domain encoding gene in M. …

1H NMR structural and functional characterisation of a cAMP-specific phosphodiesterase-4D5 (PDE4D5) N-terminal region peptide that disrupts PDE4D5 interaction …

KJ Smith, GS Baillie, EI Hyde, X Li, TM Houslay… - Cellular signalling, 2007 - Elsevier
… We suggest that the binding of PDE4D5 to the WD-repeat protein, RACK1, may occur in a
manner akin to the helix–helix interaction shown for G γ binding to the WD-repeat protein, G β . …

Functional characterisation of ClpP mutations conferring resistance to acyldepsipeptide antibiotics in Firmicutes

IT Malik, R Pereira, MT Vielberg, C Mayer… - …, 2020 - Wiley Online Library
… aureus ClpP proteins characterised in this study were functionally impaired; this increased
our understanding of the mode of operation of ClpP. For molecular insights, crystal structures …

Isolation and analysis of candidate ascochyta blight defence genes in chickpea. Part I. Generation and analysis of an expressed sequence tag (EST) library

TE Coram, ECK Pang - Physiological and Molecular Plant Pathology, 2005 - Elsevier
… After clustering, unigenes were functionally characterised and … characterised protein from
this group is the transcription factor EREBP-1 (Ethylene Responsive Element Binding Protein), …