Altered lymphatic vessel anatomy and markedly diminished lymph clearance in affected hands of patients with active rheumatoid arthritis

RD Bell, H Rahimi, HM Kenney… - Arthritis & …, 2020 - Wiley Online Library
… potential utility of NIR/ICG imaging results as a biomarker of disease. Additional investigations
into the mechanisms that promote or restrict lymphatic flow from synovial tissue have the …

Targeting lymphatic function in cardiovascular-kidney-metabolic syndrome: preclinical methods to analyze lymphatic function and therapeutic opportunities

JWM Fowler, LJ Song, K Tam… - Frontiers in …, 2024 - frontiersin.org
… to calculate lymphatic pressure when … of lymphatic function in humans would bring more
confidence into applying the same measurement for investigating functional mechanisms in mice…

The role of lymphatic vessels in the heart

Y Cui - Pathophysiology, 2010 - Elsevier
… the underlying mechanism of these effects imposed by cardiac lymph … both animal model
systems and imaging technologies. … and imaging technologies for the study of cardiac lymphatic

Lymphatic contractile function: a comprehensive review of drug effects and potential clinical application

PS Russell, J Hong, NL Trevaskis… - Cardiovascular …, 2022 - academic.oup.com
mechanism that resembles that of the heart. These shared cardiovascular (CV) mechanisms
… effects and drug interactions that impact the lymphangion and lymphatic contractile function. …

Lymph flow induces the postnatal formation of mature and functional meningeal lymphatic vessels

L Bálint, Z Ocskay, BA Deák, P Aradi… - Frontiers in …, 2020 - frontiersin.org
… Here, we aimed at characterizing the lymph flow dependence of the developmental program
and function of the meningeal lymphatics. First, we demonstrated that lymphatics present in …

Lymphatic collecting vessel: New perspectives on mechanisms of contractile regulation and potential lymphatic contractile pathways to target in obesity and metabolic …

Y Lee, SD Zawieja, M Muthuchamy - Frontiers in Pharmacology, 2022 - frontiersin.org
… activity required for active lymph propulsion and lymph return in humans. … lymphatic
architecture and collecting vessel function, including recent advances in the ionic basis of lymphatic

Lymphatic network in atherosclerosis: the underestimated path

A Milasan, J Ledoux, C Martel - Future science OA, 2015 - Taylor & Francis
… on work depicting the functional mechanisms of this complex … To properly determine whether
lymphatics are active players … observations and lymph composition with functional studies. …

Engineering the lymphatic system

ME Nipper, JB Dixon - Cardiovascular engineering and technology, 2011 - Springer
… and will help guide experiments as we seek to understand the intrinsic mechanisms that
ensure proper lymphatic function. However, in their current state, the predictive power of these …

[HTML][HTML] The lymphatic system in the brain clearance mechanisms-new therapeutic perspectives for Alzheimer's disease

A Chachaj, K Gąsiorowski, A Szuba… - Current …, 2023 - ncbi.nlm.nih.gov
… recent findings on the role of lymphatic system in the pathophysiology of AD. We also
discuss possible new therapeutic strategies associated with lymphatic clearance mechanisms. …

Animal models for the molecular and mechanistic study of lymphatic biology and disease

WS Shin, SG Rockson - Annals of the New York Academy of …, 2008 - Wiley Online Library
… Our understanding of the molecular mechanisms underlying embryonic lymphatic development
and disease has paralleled, and been facilitated by, the generation of genetic animal …