Comparative transcriptional and functional profiling of clear cell and papillary renal cell carcinoma

J Diegmann, S Tomiuk… - International …, 2006 - spandidos-publications.com
… Renal cell carcinoma (RCC) is known to effectively prevent immune recognition. … and
functional profiling with cDNA microarrays (1070 cDNA probes) on a total of 17 RCCs, 11 clear cell

[HTML][HTML] Expression profiling of human renal carcinomas with functional taxonomic analysis

MA Gieseg, T Cody, MZ Man, SJ Madore, MA Rubin… - BMC …, 2002 - Springer
profiles of renal cell carcinomas (RCCa) using the Affymetrix GeneChip platform, comparing
mRNA expression profiles … , nine clear cell carcinomas (CC), two chromophobe carcinomas (…

[HTML][HTML] MicroRNA expression profiling in clear cell renal cell carcinoma: identification and functional validation of key miRNAs

H He, L Wang, W Zhou, Z Zhang, L Wang, S Xu… - PloS one, 2015 - journals.plos.org
… miRNAs in renal cell carcinoma, we performed qRT-PCR analysis in an additional cohort of
15 ccRCC tumor samples (5 GI, 5 GII, and 5GIII), the human kidney carcinoma cell line 786-O…

Global functional profiling of gene expression

S Drǎghici, P Khatri, RP Martins, GC Ostermeier… - Genomics, 2003 - Elsevier
… at the functional profile described above, we might conclude that substance X may be related
to cancer since mitosis, oncogenesis, and cell … Now, the functional profile appears to be …

Genomic profiling in renal cell carcinoma

N Dizman, EJ Philip, SK Pal - Nature Reviews Nephrology, 2020 - nature.com
… safety profile. Clinical trials of tazemetostat in patients with solid tumours bearing EZH2
gain-of-function mutations, including renal medullary carcinoma, are currently underway 81,82 . …

[HTML][HTML] Identification of key genes and pathways in renal cell carcinoma through expression profiling data

X Liu, J Wang, G Sun - Kidney and Blood Pressure Research, 2015 - karger.com
Background/Aims: To isolate key genes and pathways in renal cell carcinoma (RCC), which
might reveal more evidences on the regulation network and contribute to pathogenic …

Functional evidence that Drosha overexpression in cervical squamous cell carcinoma affects cell phenotype and microRNA profiles

B Muralidhar, D Winder, M Murray… - The Journal of …, 2011 - Wiley Online Library
… As the most significantly differentially expressed 5p gene was Drosha, we sought to
investigate the functional consequences of overexpression of this gene in cervical SCC cells. We …

Metabolic profiling reveals key metabolic features of renal cell carcinoma

G Catchpole, A Platzer, C Weikert… - Journal of cellular …, 2011 - Wiley Online Library
functional role and render the tumour cell resistant to increased oxidative stress toxic to
surrounding normal cell … is likely not limited to its antioxidant function, but can rather be extended …

[HTML][HTML] Microarray gene expression profiling and analysis in renal cell carcinoma

LS Liou, T Shi, ZH Duan, P Sadhukhan, SD Der… - BMC urology, 2004 - Springer
… The analysis of the expression profiles of genes in the annotated functional groups provides
insights into biological pathways of RCC. Moreover, comparison of expression patterns in …

[PDF][PDF] Functional genomics of hepatocellular carcinoma

SS Thorgeirsson, JS Lee, JW Grisham - Hepatology, 2006 - Wiley Online Library
profiling studies on human hepatocellular carcinoma (HCC) … factors embedded in gene
expression profile data. However, … regulatory modules in the expression profiles. The success of …