Functional regions of the peroxin Pex19 necessary for peroxisome biogenesis

G Agrawal, HH Shang, ZJ Xia, S Subramani - Journal of Biological …, 2017 - ASBMB
… PMP-binding domains of Pex19 has provided novel insights into the modular architecture
of Pex19. We define the minimum region of Pex19 required for peroxisome biogenesis and a …

Insights into peroxisome function from the structure of PEX3 in complex with a soluble fragment of PEX19

F Schmidt, N Treiber, G Zocher, S Bjelic… - Journal of biological …, 2010 - ASBMB
… The human peroxins PEX3 and PEX19PEX19, we solved the structure of a soluble
domain of PEX3 in complex with a peptide corresponding to an N-terminal region of PEX19 (PEX19

Functional domain mapping of peroxin Pex19p: interaction with Pex3p is essential for function and translocation

Y Matsuzono, T Matsuzaki, Y Fujiki - Journal of cell science, 2006 - journals.biologists.com
… We earlier cloned human PEX19 cDNA encoding the 299 amino acid, hydrophilic peroxin
membrane biogenesis, we first searched for functional regions of Pex19p. We verified various …

Arabidopsis PEX19 is a dimeric protein that binds the peroxin PEX10

DA Hadden, BA Phillipson, KA Johnston… - Molecular membrane …, 2006 - Taylor & Francis
… Peroxisomes import integral membrane proteins post-translationally, and PEX19 is a …
We report the characterisation of the Arabidopsis thaliana homologue of PEX19 which is a …

The role of conserved PEX3 regions in PEX19‐binding and peroxisome biogenesis

F Schmidt, D Dietrich, R Eylenstein, Y Groemping… - Traffic, 2012 - Wiley Online Library
… The human peroxins PEX3 and PEX19 are essential for peroxisome biogenesis. They
mediate the import of membrane proteins as well as the de novo formation of peroxisomes. …

The peroxisome biogenesis factors Pex3 and Pex19: multitasking proteins with disputed functions

RLM Jansen, IJ van der Klei - FEBS letters, 2019 - Wiley Online Library
… only two highly conserved peroxins, Pex3 and Pex19, have been … Detailed knowledge of
the function of these two peroxins as … on yeast Pex3 and Pex19 functions and present a critical …

Identification and characterization of the human peroxin PEX3

M Soukupova, C Sprenger, K Gorgas… - European journal of cell …, 1999 - Elsevier
… To further map regions of PEX3 which would interact with PEX19 we constructed plasmids
expressing the PEX3 truncations given in Table II. None of the truncations investigated …

[HTML][HTML] Peroxisome biogenesis, protein targeting mechanisms and PEX gene functions in plants

LL Cross, HT Ebeed, A Baker - … et Biophysica Acta (BBA)-Molecular Cell …, 2016 - Elsevier
… 3 peroxins, PEX3, PEX19 and PEX16. In Saccharomyces cerevisiae mutants of PEX3 and
PEX19 … In mammalian cells an additional peroxin, PEX16, which is absent in S. cerevisiae, is …

Two splice variants of human PEX19 exhibit distinct functions in peroxisomal assembly

PU Mayerhofer, T Kattenfeld, AA Roscher… - … and biophysical research …, 2002 - Elsevier
… Among these PEX19 is the only peroxin known to own a C-terminal CAAX-box, thereby … ,
the definition of functional regions of PEX19 by the characterization of truncated PEX19 splice …

Pex19p, a farnesylated protein essential for peroxisome biogenesis

K Götte, W Girzalsky, M Linkert… - … and Cellular Biology, 1998 - Taylor & Francis
… Five of the peroxins have been shown to fulfill a function in PTS1- and PTS2-dependent …
of the PEX19 gene and the identification and characterization of the PEX19 gene product. …