Synthetic and medicinal perspective of fused-thiazoles as anticancer agents

S Pawar, K Kumar, MK Gupta… - Anti-Cancer Agents in …, 2021 - ingentaconnect.com
… profile as an anticancer agent. Various synthetic strategies for fused thiazole are also …
In this review, we will elaborate various types of fused thiazole as an anticancer agent. …

[HTML][HTML] Fused thiopyrano [2, 3-d] thiazole derivatives as potential anticancer agents

A Kryshchyshyn, D Atamanyuk, R Lesyk - Scientia pharmaceutica, 2012 - ncbi.nlm.nih.gov
… for anticancer profile optimization of chromeno[4′,3′:4,5]thiopyrano[2,3-d]thiazoles. …
of our work may be used for planning the directed synthesis of potential anticancer agents. …

One-pot synthesis of novel thiazoles as potential anti-cancer agents

AR Sayed, SM Gomha, EA Taher… - Drug design …, 2020 - Taylor & Francis
… effective and less toxic chemotherapeutic agents for the treatment … antitumor inhibitors due
to induction of oxidative stress and ROS-mediated cell injury. Citation11,Citation12 Thiazole

Thiazole and related heterocyclic systems as anticancer agents: A review on synthetic strategies, mechanisms of action and SAR Studies

K Kaur, V Jaitak - Current medicinal chemistry, 2022 - ingentaconnect.com
… Benzothiazole is a heterocyclic ring system that involves a benzene ring fused to a thiazole
moiety possessing an extensive range of biological activities, including anticancer [47]. The …

… novel DNA binding agent via design and synthesis of new thiazole hybrids and fused 1, 2, 4-triazines as potential antitumor agents: Computational, spectrometric and …

MH El-Wakil, AF El-Yazbi, HMA Ashour, MA Khalil… - Bioorganic …, 2019 - Elsevier
antitumor 1,2,4-triazine derivatives [13], [14], [15], [16], [17], [18], [19], we suggested to explore
the effect of fused … 1,2,4-triazines on the anticipated antitumor activities together with newly …

Oxygen-and sulphur-containing heterocyclic compounds as potential anticancer agents

H Sachdeva, S Khaturia, M Saquib, N Khatik… - Applied Biochemistry …, 2022 - Springer
anticancer drugs which may show promising anticancer effects with fewer side effects.
Furthermore, fused heterocycles behave as DNA intercalating agents … is a thiazole-containing …

Design, efficient synthesis and molecular docking of some novel thiazolyl-pyrazole derivatives as anticancer agents

AR Sayed, SM Gomha, FM Abdelrazek, MS Farghaly… - BMC chemistry, 2019 - Springer
… Pyrazoles, thiazoles and fused thiazoles have been reported to possess many biological
activities. 3-Methyl-5-oxo-4-(2-arylhydrazono)-4,5-dihydro-1H-pyrazole-1-carbothioamides 3a,…

A comprehensive review on thiazole based conjugates as anti-cancer agents

R Rana, N Kumar, HK Gulati, A Sharma… - Journal of Molecular …, 2023 - Elsevier
anticancer activity, and great efficacy. This review summarises recent findings on thiazoles
and … significance in the development of anticancer drugs, structure activity relationship (SAR) …

Design, synthesis and anticancer evaluation of isoxazole fused thiazole-oxazole derivatives

AK Lingala, T Mothe, KK Murahari, JR Desireddi… - Chemical Data …, 2022 - Elsevier
… These results were compared with known chemotherapeutic agentfused thiazole-oxazole
compounds (10a-j). All these derivatives were examined for their preliminary anticancer

Discovery of thiazole-based-chalcones and 4-hetarylthiazoles as potent anticancer agents: Synthesis, docking study and anticancer activity

TA Farghaly, GS Masaret, ZA Muhammad… - Bioorganic chemistry, 2020 - Elsevier
… synthesis of anticancer agents with … thiazole-based chalcones and chalcone analogs by
replacing the enone moiety with pyrimidine or fused pyrimidine rings to evaluate their antitumor