Peripheral galanin receptor 2 as a target for the modulation of pain
RP Hulse, LF Donaldson… - Pain research and …, 2012 - Wiley Online Library
… of galanin receptors on primary afferent nociceptors as … galanin receptors in the central
nervous system, functional studies demonstrated that galanin could modulate spinal nociceptive …
nervous system, functional studies demonstrated that galanin could modulate spinal nociceptive …
[HTML][HTML] A new gal in town: a systematic review of the role of galanin and its receptors in experimental pain
D Fonseca-Rodrigues, A Almeida, F Pinto-Ribeiro - Cells, 2022 - mdpi.com
… The role of galanin in nociceptive modulation has been intensively investigated using …
insufficient galaninergic control of nociception, targeting galanin receptors (particularly GalR1) …
insufficient galaninergic control of nociception, targeting galanin receptors (particularly GalR1) …
Activation of peripheral galanin receptors: differential effects on nociception
JM Jimenez-Andrade, L Lundström… - Pharmacology …, 2006 - Elsevier
… To determine if high doses of peripheral GAL modulated CAP-induced nociception, male
Wistar rats received intraplantar injections of 10 μl 0.1% CAP + 20 μl saline or 10 μl 0.1% CAP …
Wistar rats received intraplantar injections of 10 μl 0.1% CAP + 20 μl saline or 10 μl 0.1% CAP …
[HTML][HTML] Involvement of galanin and galanin receptor 1 in nociceptive modulation in the central nucleus of amygdala in normal and neuropathic rats
SY Li, ML Huo, XY Wu, YQ Huang, L Wang, X Zhang… - Scientific Reports, 2017 - nature.com
… the role of galanin and galanin receptor 1 (GalR 1) in nociceptive modulation in the central
… -dependent manner after intra-CeA injection of galanin in both normal rats and rats with …
… -dependent manner after intra-CeA injection of galanin in both normal rats and rats with …
Differential roles of galanin on mechanical and cooling responses at the primary afferent nociceptor
… Mechanically evoked responses in C-fibre nociceptors from naive rats … galanin or Gal2-11
(a galanin receptor-2/3 agonist) confirming previous data that galanin modulates nociception …
(a galanin receptor-2/3 agonist) confirming previous data that galanin modulates nociception …
Pro-nociceptive role of peripheral galanin in inflammatory pain
JM Jimenez-Andrade, S Zhou, J Du, A Yamani… - Pain, 2004 - Elsevier
… In summary, our findings suggest that peripheral GAL modulates VR1 function and has
an excitatory role under acute inflammatory conditions. This excitatory effect is likely to be …
an excitatory role under acute inflammatory conditions. This excitatory effect is likely to be …
Galanin plays a role in antinociception via binding to galanin receptors in the nucleus accumbens of rats with neuropathic pain
Y Zhang, Y Gao, CY Li, W Dong, MN Li, YN Liu… - Neuroscience …, 2019 - Elsevier
… Galanin and galanin receptors (GalRs) play important roles in the transmission and
modulation of nociceptive information. Our previous research has shown that the expression of …
modulation of nociceptive information. Our previous research has shown that the expression of …
[PDF][PDF] Galanin receptor 1 plays an antinociceptive effect via inhibiting PKA activation in the nucleus accumbens of rats with neuropathic pain
Y Zhang, Y Gao, CY Li, W Dong, Y Dong… - Physiological …, 2019 - biomed.cas.cz
… ZHANG ML, WANG HB, FU FH, YU LC: Involvement of galanin and galanin receptor 2 in
nociceptive modulation in anterior cingulate cortex of normal rats and rats with mononeuropathy…
nociceptive modulation in anterior cingulate cortex of normal rats and rats with mononeuropathy…
Activation of the galanin receptor 2 in the periphery reverses nerve injury-induced allodynia
… the anti-nociceptive actions of galanin are principally … by each galanin receptor subtype
in nociceptive processing in … activation of GalR2 can modulate nociceptive C-fibre afferent …
in nociceptive processing in … activation of GalR2 can modulate nociceptive C-fibre afferent …
Interactions of galanin and opioids in nociceptive modulation in the arcuate nucleus of hypothalamus in rats
YG Sun, LC Yu - Regulatory peptides, 2005 - Elsevier
… galanin in a dose-dependent manner, while the δ-opioid receptor antagonist naltrindole or
the κ-opioid receptor … Moreover, intra-ARC injection of a galanin receptor antagonist galantide …
the κ-opioid receptor … Moreover, intra-ARC injection of a galanin receptor antagonist galantide …
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