Elevated galectin-3 precedes the development of CKD
… risk prediction based on reclassification indices. In conclusion, elevated levels of plasma
galectin-3 are associated with increased risks … which calls for further study in higher-risk groups. …
galectin-3 are associated with increased risks … which calls for further study in higher-risk groups. …
The fibrosis marker galectin‐3 and outcome in the general population
RA De Boer, DJ Van Veldhuisen… - Journal of internal …, 2012 - Wiley Online Library
… galectin-3 levels are associated with increased risk of mortality. Unadjusted analyses
showed that, in particular, subjects in the highest quintile of galectin-3 have an increased risk of …
showed that, in particular, subjects in the highest quintile of galectin-3 have an increased risk of …
Galectin-3: a modifiable risk factor in heart failure
RA de Boer, AR van der Velde, C Mueller… - … drugs and therapy, 2014 - Springer
… galectin-3 is important in the development of HF has come from epidemiological data. Galectin-3
… , and elevated plasma galectin-3 levels strongly predict risk of the development of HF in …
… , and elevated plasma galectin-3 levels strongly predict risk of the development of HF in …
Increased levels of galectin-3 were associated with prediabetes and diabetes: new risk factor?
… our study, Gal-3 levels are significantly increased in prediabetic and diabetic patients. Gal-3
is … Based on our results, we suggest that increasing levels of Gal -3 are a biomarker that may …
is … Based on our results, we suggest that increasing levels of Gal -3 are a biomarker that may …
Galectin-3 predicts long-term cardiovascular death in high-risk patients with coronary artery disease
G Maiolino, G Rossitto, L Pedon, M Cesari… - … , and vascular biology, 2015 - Am Heart Assoc
… high cardiovascular risk patients referred … Gal-3 levels predict cardiovascular deaths and
events during long-term follow-up by giving due consideration to many other cardiovascular risk …
events during long-term follow-up by giving due consideration to many other cardiovascular risk …
Galectin-3 and incidence of atrial fibrillation: The Atherosclerosis Risk in Communities (ARIC) study
… In conclusion, high galectin-3 levels are associated with an increased incidence of AF in
the general population via pathways seemingly involving CHD and HF. The LGALS3 rs4644 …
the general population via pathways seemingly involving CHD and HF. The LGALS3 rs4644 …
Galectin‐3 and risk of heart failure and death in blacks and whites
… Our results extend the literature in this field, particularly as prior reports of galectin‐3 as a
risk factor for incident outcomes were all derived from cohorts comprised almost exclusively of …
risk factor for incident outcomes were all derived from cohorts comprised almost exclusively of …
Galectin‐3 and risk of cardiovascular events and all‐cause mortality in type 2 diabetes
… of galectin-3 can reduce atherosclerotic lesions and slow atherosclerotic plaque progression
in mouse models.13, 14 In high risk patients with coronary heart disease, galectin-3 level …
in mouse models.13, 14 In high risk patients with coronary heart disease, galectin-3 level …
Galectin-3 is associated with heart failure incidence: a meta-analysis
… to bottom-quartile log-galectin3 and the risk of heart failure. Adjusted meta-analysis presents
a 32% higher HF risk in individuals with top-quartile log-galectin-3 levels than in the bottom …
a 32% higher HF risk in individuals with top-quartile log-galectin-3 levels than in the bottom …
Serial galectin-3 and future cardiovascular disease in the general population
AR van der Velde, WC Meijers, JE Ho, FP Brouwers… - Heart, 2016 - heart.bmj.com
… In age-adjusted and sex-adjusted analyses, persistently elevated galectin-3 levels were
still associated with an increased risk for new-onset HF and CV mortality (table 2, see online …
still associated with an increased risk for new-onset HF and CV mortality (table 2, see online …
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