Elevated galectin-3 precedes the development of CKD

CM O'Seaghdha, SJ Hwang, JE Ho… - Journal of the …, 2013 - journals.lww.com
risk prediction based on reclassification indices. In conclusion, elevated levels of plasma
galectin-3 are associated with increased risks … which calls for further study in higher-risk groups. …

The fibrosis marker galectin3 and outcome in the general population

RA De Boer, DJ Van Veldhuisen… - Journal of internal …, 2012 - Wiley Online Library
galectin-3 levels are associated with increased risk of mortality. Unadjusted analyses
showed that, in particular, subjects in the highest quintile of galectin-3 have an increased risk of …

Galectin-3: a modifiable risk factor in heart failure

RA de Boer, AR van der Velde, C Mueller… - … drugs and therapy, 2014 - Springer
galectin-3 is important in the development of HF has come from epidemiological data. Galectin-3
… , and elevated plasma galectin-3 levels strongly predict risk of the development of HF in …

Increased levels of galectin-3 were associated with prediabetes and diabetes: new risk factor?

H Yilmaz, M Cakmak, O Inan, T Darcin… - Journal of …, 2015 - Springer
… our study, Gal-3 levels are significantly increased in prediabetic and diabetic patients. Gal-3
is … Based on our results, we suggest that increasing levels of Gal -3 are a biomarker that may …

Galectin-3 predicts long-term cardiovascular death in high-risk patients with coronary artery disease

G Maiolino, G Rossitto, L Pedon, M Cesari… - … , and vascular biology, 2015 - Am Heart Assoc
… high cardiovascular risk patients referred … Gal-3 levels predict cardiovascular deaths and
events during long-term follow-up by giving due consideration to many other cardiovascular risk

Galectin-3 and incidence of atrial fibrillation: The Atherosclerosis Risk in Communities (ARIC) study

OE Fashanu, FL Norby, D Aguilar, CM Ballantyne… - American heart …, 2017 - Elsevier
… In conclusion, high galectin-3 levels are associated with an increased incidence of AF in
the general population via pathways seemingly involving CHD and HF. The LGALS3 rs4644 …

Galectin3 and risk of heart failure and death in blacks and whites

JW McEvoy, Y Chen, MK Halushka… - Journal of the …, 2016 - Am Heart Assoc
… Our results extend the literature in this field, particularly as prior reports of galectin3 as a
risk factor for incident outcomes were all derived from cohorts comprised almost exclusively of …

Galectin3 and risk of cardiovascular events and all‐cause mortality in type 2 diabetes

KCB Tan, CL Cheung, ACH Lee… - Diabetes/metabolism …, 2019 - Wiley Online Library
… of galectin-3 can reduce atherosclerotic lesions and slow atherosclerotic plaque progression
in mouse models.13, 14 In high risk patients with coronary heart disease, galectin-3 level …

Galectin-3 is associated with heart failure incidence: a meta-analysis

BM Baccouche, MA Mahmoud, C Nief… - Current Cardiology …, 2023 - ingentaconnect.com
… to bottom-quartile log-galectin3 and the risk of heart failure. Adjusted meta-analysis presents
a 32% higher HF risk in individuals with top-quartile log-galectin-3 levels than in the bottom …

Serial galectin-3 and future cardiovascular disease in the general population

AR van der Velde, WC Meijers, JE Ho, FP Brouwers… - Heart, 2016 - heart.bmj.com
… In age-adjusted and sex-adjusted analyses, persistently elevated galectin-3 levels were
still associated with an increased risk for new-onset HF and CV mortality (table 2, see online …