Gallic acid improved inflammation via NF-κB pathway in TNBS-induced ulcerative colitis

L Zhu, PQ Gu, H Shen - International immunopharmacology, 2019 - Elsevier
Gallic acid efficiently suppressed NF-κB signaling pathway in TNBS-induced UC. …
Gallic acid plays an anti-inflammatory role in UC via inhibiting NF-κB pathway. …

Terminalia bellirica (Gaertn.) Roxb. Extract and Gallic Acid Attenuate LPS‐Induced Inflammation and Oxidative Stress via MAPK/NFκB and Akt/AMPK/Nrf2 Pathways

M Tanaka, Y Kishimoto, M Sasaki… - Oxidative Medicine …, 2018 - Wiley Online Library
Excessive oxidative stress plays a critical role in the progression of various diseases. Recently,
we showed that Terminalia bellirica (Gaertn.) Roxb. extract (TBE) inhibits inflammatory …

Gallic Acid-g-Chitosan Modulates Inflammatory Responses in LPS-Stimulated RAW264.7 Cells Via NF-κB, AP-1, and MAPK Pathways

CB Ahn, WK Jung, SJ Park, YT Kim, WS Kim, JY Je - Inflammation, 2016 - Springer
… However, our GAC prepared in this study is soluble in water due to grafting of gallic acid onto
chitosan. This is the main advantage compared to unmodified chitosan with high molecular …

Anti-metastasis effects of gallic acid on gastric cancer cells involves inhibition of NF-κB activity and downregulation of PI3K/AKT/small GTPase signals

HH Ho, CS Chang, WC Ho, SY Liao, CH Wu… - Food and Chemical …, 2010 - Elsevier
… been focused on phenolic acids. In this study, the aim was to investigate the effect of … acids
found abundantly in vegetables, ie gallic acid (GA), caffeic acid (CA) and protocatechuic acid (…

Gallic acid inhibits gastric cancer cells metastasis and invasive growth via increased expression of RhoB, downregulation of AKT/small GTPase signals and inhibition …

HH Ho, CS Chang, WC Ho, SY Liao, WL Lin… - Toxicology and applied …, 2013 - Elsevier
… of PI3K and AKT in AGS cells treated with gallic acid (GA). AGS cells were transfected with
… of the expression of IκB and NF-κB in AGS cells treated with gallic acid (GA). AGS cells were …

Gallic acid mitigates LPS‐induced inflammatory response via suppressing NFκB signalling pathway in IPEC‐J2 cells

L Cai, Z Wei, X Zhao, Y Li, X Li… - Journal of Animal …, 2022 - Wiley Online Library
… -1) and occludin, while pretreatment with gallic acid preserved expression level of tight
junction … , gallic acid may mitigate LPS-induced inflammatory responses by inhibiting the NF-κB

Gallic acid suppresses lipopolysaccharide-induced nuclear factor-κB signaling by preventing RelA acetylation in A549 lung cancer cells

KC Choi, YH Lee, MG Jung, SH Kwon, MJ Kim… - Molecular Cancer …, 2009 - AACR
… To confirm the prevention of p300-mediated p65 acetylation by gallic acid, we next assessed
the effect of gallic acid treatment on LPS-induced acetylation of p65 in A549 lung cancer …

Suppression of TNF-α induced NFκB activity by gallic acid and its semi-synthetic esters: possible role in cancer chemoprevention

MCC Morais, S Luqman, TP Kondratyuk… - Natural Product …, 2010 - Taylor & Francis
… In the present investigation, gallic acid was isolated from Alchornea glandulosa Poepp and
Endl. (Euphorbiaceae), and eight semi-synthetic esters were prepared. All the compounds …

Anti-leukemic effects of gallic acid on human leukemia K562 cells: Downregulation of COX-2, inhibition of BCR/ABL kinase and NF-κB inactivation

TC Reddy, DB Reddy, A Aparna, KM Arunasree… - Toxicology in Vitro, 2012 - Elsevier
Gallic acid (GA) induces apoptosis in various cancer cell lines. In this study, we investigated
the apoptotic activity induced by GA on chronic myeloid leukemia (CML) cell line-K562 and …

Gallic acid inhibits migration and invasion of SCC‑4 human oral cancer cells through actions of NFκB, Ras and matrix metalloproteinase-2 and-9

CL Kuo, KC Lai, YS Ma, SW Weng… - Oncology …, 2014 - spandidos-publications.com
Oral cancer is one of the major causes of mortality in humans and squamous cell carcinoma
is the most common type of oral cancer. Gallic acid (GA) is a natural product that induces …