… therefore that different anions, involved in complexing gallium to transferrin do play …
transferrin plays in gallium uptake by tumors is clearly illustrated. Irrespective of which 67Ga-Tf-anion …

… ) and mouse serum for the transferrin receptors. In analyzing … gallium is known to have a
toxic effect on some animal tumors [21,22], we studied the effect of stable gallium and transferrin …

… transferrin concentration, both on the binding of gallium to transferrin and on the tumor cell
uptake of gallium. … effect of glucose on gallium uptake by tumor cells both in vitro and in vivo. …

… of gallium binding by transferrin, and we have determined the macroscopic gallium binding
… transferrin. A unique feature of the transferrins is that metal bindingrequires the concomitant …

… Magnetic resonance studies of the spatial relation of the metal and anion in human transferrin,
In: Crighton RR, ed. Proteins of iron storage and transport in biochemistry and medicine. …

… Small anions would be able to diffuse to the metal ion binding site on the protein. This site is
… the metal binding site may serve to anchor the anions (26), thereby allowing them to disrupt …

… This requirement of a synergistic carbonate anion for metal binding is often considered to …
This review focuses on transferrin binding of the Group 13 metal ions, aluminum(III), gallium(III)…

… “‘Ga-transferrin competes with non-labelled transferrin for binding to tumor cell associated
… the presence of certain anions. This interdependence of metal and anion binding is said to …

… gallium-transferrin complex. The object of our study was to investigate the role of transferrin
… ,” ‘i and that the presence of either bicarbonate or carbonate anion acts as a bridging ligand …

… characteristics of three preparations of the gallium-transferrin complex in rat plasma. …
An anion, such as HCO; is required to make gallium-transferrin binding possible. Galliumtransferrin …