Gallium-transferrin as a macromolecular tracer of vascular permeability
A Brunetti, RG Blasberg, RD Finn, SM Larson - International Journal of …, 1988 - Elsevier
… whether the gallium-transferrin complex could be effectively used as a macromolecular
tracer in … Three gallium-plasma preparations were tested and 2 h biodistribution studies were …
tracer in … Three gallium-plasma preparations were tested and 2 h biodistribution studies were …
[PDF][PDF] Comparison of iron-59, indium-111, and gallium-69 transferrin as a macromolecular tracer of vascular permeability and the transferrin receptor
H Otsuki, A Brunetti, ES Owens, RD Finn… - Journal of nuclear …, 1989 - Soc Nuclear Med
… that iron, indium, and gallium in tracer amounts were quickly and almost completely bound
to plasma proteins or formed macromolecular aggregates. The retention fraction ofthe [Fe3], […
to plasma proteins or formed macromolecular aggregates. The retention fraction ofthe [Fe3], […
Thermodynamic binding constants for gallium transferrin
WR Harris, VL Pecoraro - Biochemistry, 1983 - ACS Publications
… of gallium binding by transferrin, and we have determined the macroscopic gallium binding
… transferrin. A unique feature of the transferrins is that metal bindingrequires the concomitant …
… transferrin. A unique feature of the transferrins is that metal bindingrequires the concomitant …
The role of transferrins in gallium uptake
SM Larson, Z Grunbaumi, JS Raseyz - International Journal of Nuclear …, 1981 - Elsevier
… to other subcellular macromolecules. Also, iron and … to gallium-transferrin in the blood, and
the gallium-transferrin … tracer amounts of iodinated mouse transferrin were added to these …
the gallium-transferrin … tracer amounts of iodinated mouse transferrin were added to these …
Evaluation of Gallium as a Tracer of Exogenous Hemoglobin–Haptoglobin Complexes for Targeted Drug Delivery Applications
S Xu, IA Kaltashov - Journal of The American Society for Mass …, 2016 - ACS Publications
… of nonferrous metals as potential in vivo tracers of transferrin-based therapeutics J. Am. Soc.
… Gas-phase processes and measurements of macromolecular properties in solution: on the …
… Gas-phase processes and measurements of macromolecular properties in solution: on the …
[PDF][PDF] Effect of bicarbonate on stability of the gallium-transferrin complex
BL Staker, MM Graham, ML Evans - Journal of Nuclear Medicine, 1991 - Soc Nuclear Med
… Comparisons of iron-59, indium-l I1,and galliurn-68 transferrin asa macromolecular
tracer of vascular permeability and the transferrin receptor. J Nud Med 1989:30:1676—1685. …
tracer of vascular permeability and the transferrin receptor. J Nud Med 1989:30:1676—1685. …
Common pathway for tumor cell uptake of gallium-67 and iron-59 via a transferrin receptor
SM Larson, JS Rasey, DR Allen… - Journal of the …, 1980 - academic.oup.com
… rapidly saturates binding and effectively abolishes concentration of tracer 67 Ga. Hegge et
al… with the observed uptake of gallium and iron. We found a macromolecular component of the …
al… with the observed uptake of gallium and iron. We found a macromolecular component of the …
Evaluation of nonferrous metals as potential in vivo tracers of transferrin-based therapeutics
… result in preferential retention of macromolecules via enhanced … routing are frequently
overlooked is transferrin (Tf), an 80 kDa … noncognate metals (indium and gallium), the interaction …
overlooked is transferrin (Tf), an 80 kDa … noncognate metals (indium and gallium), the interaction …
The transferrin-receptor hypothesis: mechanism of tumor uptake of carrier-free gallium-67
SM Larson, JS Rasey, DR Allen - Frontiers in Nuclear Medicine, 1980 - Springer
… of tracer 67Ga. In earlier work [37], it was shown that after IV administration, 67Ga, like 59Fe,
was incorporated into ferritin in rabbit liver. Some of these gallium-binding macromolecules …
was incorporated into ferritin in rabbit liver. Some of these gallium-binding macromolecules …
[PDF][PDF] Mechanism of gallium-67 accumulation in tumors
MF Tsan, U Scheffel - Journal of nuclear medicine, 1986 - Soc Nuclear Med
… entry and residency time of macromolecules in the interstitial space … transferrin and [67Gajcitrate.
Since after iv injection of [67Ga]citrate 99% of the tracer is bound to plasma transferrin (8…
Since after iv injection of [67Ga]citrate 99% of the tracer is bound to plasma transferrin (8…
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