Gallium (Ga) is the second metal ion, after platinum, to be used in cancer treatment. Its activities
are numerous and various. It modifies three-dimensional structure of DNA and inhibits its …

… was derivatized with a DOTA chelator and labeled with gallium-68. In vitro cell studies with
[… in their attachment to tracer molecules. Metal radionuclides such as gallium-68, copper-64 …

… carrier-effect on Ga distribution trace back to the first investigation … of the galliumtransferrin
complex to a transferrin receptor … and gallium are bound within the cells to macromolecules …

… tracers as PET tracers is studied with animal experiments. … when linked to a macromolecule.
The chelator should be … than that of the 68Ga-transferrin complex to avoid any premature …

… Table 1, summarizes a list of BPI tracers with their properties. … to serum proteins (such as
transferrin). However, the release is very slight and complex is majorly (>90%) intact in 120 min. …

… transferrin also clears slowly from the blood. The gallium is bound within the iron-binding
sites of transferrin… case for bifunctional chelators and macromolecules, the optimisation needs …

… , as intravenous injection of free 68 Ga(III) predominantly results in transferrin-bound
activity [14–17]. In contrast, both bisphosphonate tracers 68 Ga-TRAP(MDP) 3 and 68 Ga-TRAP(…

… their uptake of gallium with excess transferrin. Our results … concentrations of gallium nitrate
with 67 Ga as a tracer. When … binding to different ligands/macromolecules, thereby leading to …

… with a small amount of 67Gato serve as a tracer for Ga3 @ … per molecule of transferrin. Because
of the racemic nature of the … monoclonal antibodies and other macromolecules in tumors. …

… were labelled with radioactive gallium or indium. Gallium complexes were generally more
… Three ^"^Ga and two min complexes showed potential as imaging agents and one gallium …