[PDF][PDF] Measurements of pulmonary vascular permeability with PET and gallium-68 transferrin

MA Mintun, DR Dennis, MJ Welch… - Journal of nuclear …, 1987 - Soc Nuclear Med
vascular permeability with positron emission tomography (PET) and gallium-68- (^Ga) labeled
transferrin… min, after in vivo labeling of transferrin through intravenous administration of [^…

Gallium-transferrin as a macromolecular tracer of vascular permeability

A Brunetti, RG Blasberg, RD Finn, SM Larson - International Journal of …, 1988 - Elsevier
… the gallium-transferrin complex could be effectively used as a macromolecular tracer in
studies of capillary permeability using Positron Emission Tomography (PET). Three gallium-…

[PDF][PDF] Comparison of iron-59, indium-111, and gallium-69 transferrin as a macromolecular tracer of vascular permeability and the transferrin receptor

H Otsuki, A Brunetti, ES Owens, RD Finn… - Journal of nuclear …, 1989 - Soc Nuclear Med
… ]transferrin have been used to measure pulmonary vascular … result of increased capillary
permeability to the indium-transferrin … It is also recognized that transferrin-metal chelates are sub …

[PDF][PDF] Effect of bicarbonate on stability of the gallium-transferrin complex

BL Staker, MM Graham, ML Evans - Journal of Nuclear Medicine, 1991 - Soc Nuclear Med
… measures of vascular permeability since unbound gallium is likely to diffuse rapidly across
… high estimates of vascular permeability. The binding ofgallium to transferrin is known to …

[PDF][PDF] Mechanism of gallium-67 accumulation in tumors

MF Tsan, U Scheffel - Journal of nuclear medicine, 1986 - Soc Nuclear Med
… have shown that intramuscular injection of histamine which increases capillary permeability,
… In vitro transfer of 67Ga from transferrin to lactoferrin (13) as well as from transferrin to …

[PDF][PDF] Role of iron-binding proteins and enhanced capillary permeability on the accumulation of gallium-67

KY Tzen, ZH Oster, HN Wagner… - Journal of Nuclear …, 1980 - Soc Nuclear Med
… due to increased capillary permeability and expanded extracellular space, we studied the
effect of im injection of histamine, transferrin, or … Gallium uptake after prior saturation of the iron …

Mechanism of gallium-67 accumulation in inflammatory lesions

MF Tsan - Journal of Nuclear Medicine, 1985 - Soc Nuclear Med
Gallium-67, mainly in the form of transferrin-Ga-67 complex, … Transferrin is present in the
inflammatory lesions (50) due to leakage of plasma protein via increased vascular permeability

Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review

H Maeda, J Wu, T Sawa, Y Matsumura… - Journal of controlled …, 2000 - Elsevier
… of vascular permeability has been known and utilized for a long time in clinical radiology as
gallium scintigraphy … Radioactive gallium binds to transferrin (90 kDa), and then the gallium–…

Evaluation of nonferrous metals as potential in vivo tracers of transferrin-based therapeutics

H Zhao, S Wang, SN Nguyen, SG Elci… - Journal of The …, 2015 - ACS Publications
Transferrin (Tf) is a promising candidate for targeted drug delivery. While development of …
in this work as possible tracers of exogenous transferrin in complex biological matrices using …

Gallium: New developments and applications in radiopharmaceutics

PJ Blower, R Cusnir, A Darwesh, NJ Long… - Advances in Inorganic …, 2021 - Elsevier
gallium binding in vivo is the iron-transport protein transferrin; the ionic radii of Ga 3+ and Fe
3+ are similar, and Ga 3+ can bind to the iron-binding sites of transferrin… to transferrin during …