… Matrix Gla protein (MGP), a low molecular weight protein … acid y-carboxyglutamic acid (Gla).
We have used antibodies … K-dependent y-carboxylase recognizes substrate. The present …

… Matrix GLA protein (MGP) is an inhibitor of calcification in the arterial wall and its activity
is dependent upon vitamin K-dependent -carboxylation. This modification is carried out by a …

… We hypothesized that low endogenous production of MGP and impaired carboxylation of
MGP may contribute to the development or the progression of vascular disease. …

… ) protein (MGP), an inhibitor of … -carboxylation of MGP in the aortic wall, leading to increased
vascular calcification, and the role of γ-carboxylase and VKOR in this γ-carboxylation deficit. …

… small vitamin Kdependent bone matrix proteins, bone Gla protein (BGP) and matrix Gla
protein (MGP), to evaluate the possibility that either of these proteins might be synthesized by the …

… Matrix Gla protein (MGP), an extracellular matrix protein produced in both vascular smooth
… (4 glutamic acid residues undergoing carboxylation and 3 serine residues undergoing …

… Matrix γ-carboxyglutamate (Gla) protein (MGP) is an important local inhibitor of vascular …
γ-glutamate carboxylation and serine phosphorylation. While carboxylation is thought to have …

… Matrix Gla protein (MGP) is a potent inhibitor of vascular calcification. The ability of MGP to
… , which mediates MGP carboxylation. We investigated how MGP carboxylation influences the …

… gamma-carboxylation of the Gla proteins. … gamma-carboxylation and MGP, it was recently
reported that patients with a mutation in the gene encoding the gamma-glutamyl carboxylase …

… Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein. …
Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein. …