Gamma irradiation of human leukaemic cells HL-60 and MOLT-4 induces decrease in Mcl-1 and Bid, release of cytochrome c, and activation of caspase-8 and …

A Tichý, D Záškodová, J Pejchal… - … Journal of Radiation …, 2008 - Taylor & Francis
… We selected two representatives of Bcl-2 family (anti-apoptotic Mcl-1 – myeloid cell line-1 …
function in ionizing radiation (IR)-induced apoptosis in human leukaemic cell lines diverging in …

γRay irradiation induces B7. 1 expression in myeloid leukaemic cells

R Vereecque, G Buffenoir, R Gonzalez… - British journal of …, 2000 - Wiley Online Library
… for immunotherapy protocols would require prior irradiation of these cellsleukaemic
cell lines and in 20 ex vivo primary cultured acute myeloid leukaemic cells the effect of γ-irradiation

γ-Irradiation enhances transgene expression in leukemic cells

R Vereecque, A Saudemont, TJ Wickham, R Gonzalez… - Gene therapy, 2003 - nature.com
irradiation enhanced transgene expression in leukemic cell lines and primary cultured AML
cells… transgene expressions in irradiated leukemic cells injected subcutaneously in mice. …

Beta-irradiation used for systemic radioimmunotherapy induces apoptosis and activates apoptosis pathways in leukaemia cells

C Friesen, A Lubatschofski, J Kotzerke… - European journal of …, 2003 - Springer
… Here we report that beta-irradiation induced apoptosis in leukaemia cells involving the
receptor/ligand pathway and the mitochondrial pathway. After beta-irradiation, CD95 ligand and …

The effect of daily low dose gamma irradiation on growth and differentiation of human myeloid leukaemic bone marrow in diffusion chambers

JS Greenberger, JM Chang, V King… - Scandinavian …, 1981 - Wiley Online Library
… 12, 23, or 108 rad/d of gamma irradiation did not consistently induce differentiation of freshly
explanted human leukaemic cells in diffusion chambers. Diffusion chamber culture itself has …

Apoptosis in chronic myeloid leukaemia: normal responses by progenitor cells to growth factor deprivation, X‐irradiation and glucocorticoids

TAS Amos, JL Lewis, FH Grand… - British journal of …, 1995 - Wiley Online Library
… question of mature cell survival by growing colonies of normal and leukaemic cells in vitro
and … We were not able to find any evidence for increased leukaemic mature cell survival in this …

Radiation response of haematopoietic cell lines of human origin

S Lehnert, WB Rybka, S Suissa… - … Journal of Radiation …, 1985 - Taylor & Francis
… of the radiosensitivity of human leukaemic cells. In this contribution … of human cell lines
predominantly of leukaemic origin. … of cells from normal mouse bone marrow to gamma radiation

Molecular characterisation of murine acute myeloid leukaemia induced by 56Fe ion and 137Cs gamma ray irradiation

…, Y Peng, PN Le, LH Ding, PC Genik, FA Ray… - …, 2013 - academic.oup.com
… To identify PU.1 deletions in this study, we performed FISH analysis and aCGH using
leukaemic cells from the spleens of affected mice. PU.1 deletions were detected in all gamma ray-…

High levels of chromosome aberrations correlate with impaired in vitro radiation-induced apoptosis and DNA repair in human B-chronic lymphocytic leukaemia cells

R Blaise, C Alapetite, P Masdehors… - … journal of radiation …, 2002 - Taylor & Francis
… The kinetics of Other patients had resistant B-CLL cells in which DNA strand break rejoining
… by any B-cells of leukaemic donors were reported and comapplied dose of irradiation (n5 12)…

[PDF][PDF] Gamma-radiation-induced phosphorylation of p 53 on serine 15 is dose-dependent in molt-4 leukaemia cells

A Tichy, D Záskodová, F Zoelzer, J Vavrova… - Folia Biologica …, 2009 - fb.cuni.cz
leukaemic cell line, MOLT-4. Several studies (Lu-Hesselman et al., 2006; Marchetti et al.,
2006) have suggested p53 as a top candidate biodosimetric indicator. We propose to evaluate …