Structure of the gap junction channel and its implications for its biological functions

S Maeda, T Tsukihara - Cellular and Molecular Life Sciences, 2011 - Springer
gap junction contains clusters of tens to thousands of intercellular channels called “gap junction
channels… are essential for the formation of functional gap junction channel [3]. There are …

[HTML][HTML] Structural organization of gap junction channels

GE Sosinsky, BJ Nicholson - Biochimica et Biophysica Acta (BBA) …, 2005 - Elsevier
… the extracellular “gap”, or … gap junction channel at the molecular level so that the larger
context of these mutants can also be understood. Understanding the functionality of gap junctions

[HTML][HTML] The gap junction communication channel

NM Kumar, NB Gilula - Cell, 1996 - cell.com
… of each connexin channel account for the gap junction channel … in channel permeability is
not known. Reconstitution studies and the biophysical characterization of gap junction channel

[HTML][HTML] Selective permeability of gap junction channels

GS Goldberg, V Valiunas, PR Brink - Biochimica et Biophysica Acta (BBA) …, 2004 - Elsevier
… of how gap junctions might function in such tissues, a primary goal is to determine biophysical
properties that are most relevant to the transit of a solute through a gap junction channel

Structural and functional studies of gap junction channels

S Nakagawa, S Maeda, T Tsukihara - Current opinion in structural biology, 2010 - Elsevier
… A gap junction contains clusters of tens to thousands of intercellular channels called ‘gap
junction channels,’ which allow passage of ions and small molecules; these junctions mediate …

Molecular biology and genetics of gap junction channels

NM Kumar, NB Gilula - Seminars in cell biology, 1992 - Elsevier
… to isolate the channel containing gap junctions, and to determine from these isolated gap
junctions the polypeptide gene products that are used to produce the channel oligomers. This …

[HTML][HTML] Gap junction channel gating

FF Bukauskas, VK Verselis - Biochimica et Biophysica Acta (BBA) …, 2004 - Elsevier
Gap junction channels exhibit a property common among ion channels whereby … by
considering the configuration of the GJ channel, which, by connecting the cytoplasms of …

Gap junction channels in the cardiovascular system: pharmacological and physiological modulation

S Dhein - Trends in pharmacological sciences, 1998 - cell.com
… structure, synthesis and function of gap junction channels. Since their physiology and … gap
junctions in the heart and vasculature, with special emphasis on the regulation of the channels

Cardiac gap junction channels: modulation of expression and channel properties

TAB van Veen, HVM Van Rijen… - Cardiovascular …, 2001 - academic.oup.com
… The biochemical and electrical characteristics of gap junction channels depend on their
constituent connexins. Moreover, the properties of gap junction channels can be modulated by …

Structure of gap junction intercellular channels

M Yeager, BJ Nicholson - Current opinion in structural biology, 1996 - Elsevier
… projection density maps of different gap junction specimens, an oligomeric connexon with
a central channel is a conserved motif in the design of gap junction membrane channels [22]. …