… whether chondrocytes within the cartilage matrix have the capacity to communicate
through intercellular connections mediated by voltage-gated gap junction (GJ) channels. …

… BCs and SCs, and to determine the extent of gap junction mediated coupling, we performed
experiments on cell pairs to record junctional currents by dual whole-cell voltage clamp. Fig. …

… Synovial tissue produces synovium, a fluid that lubricates the joints and supplies nutrients
to articular chondrocytes. Alterations of this communication network are assumed to be …

… resulting in an elongated shaped with long thin cytoplasmic projection arms extending to
reach remote cells and forming a network structure of functional gap junctions which can …

… between the extracellular and intercellular networks. GJs are membrane channels that often
… if adult human chondrocytes express Cx proteins and contain functional gap junctions. The …

… importance as gap junction components, connexins are also known as gap junction proteins,
… 100% of chondrocytes in each zone; it forms gap junctions when a lacuna contains multiple …

… The present study show that chondrocytes are connected into gap junction coupled networks,
responding to Ca2+-evoked release from intracellular stores, which change in behavior …

… in the network share every signal; while some signals that diffuse through the gap
junctions … are required for the differentiation of chondrocytes, as inhibition of gap junctional …

… ) formations in chondrocytes, especially … gap junctions among chondrocytes. Furthermore,
the inhibitor of ERK attenuated the increases of Cx43 expressions and functional gap junction …

… We did not address directly whether this was also the case in BC cell networks. However,
in previous studiedz4) we have found that, in the absence of extracellular Ca2+, deformation …