Gap junctions and cochlear homeostasis

HB Zhao, T Kikuchi, A Ngezahayo, TW White - The Journal of membrane …, 2006 - Springer
… Here we review the cochlear gap junction networks and their … and physiological gating of
cochlear connexins, animal … These studies elucidate gap junction functions in the cochlea

Supporting sensory transduction: cochlear fluid homeostasis and the endocochlear potential

P Wangemann - The Journal of physiology, 2006 - Wiley Online Library
… most prominent aspects of cochlear fluid homeostasis. It covers cochlear fluid composition,
the … , the role of gap junctions, mechanisms of acid–base homeostasis, and Ca 2+ transport. …

Gap junction systems in the mammalian cochlea

T Kikuchi, RS Kimura, DL Paul, T Takasaka… - Brain research …, 2000 - Elsevier
homeostasis. Connexin 26 occurs in gap junctions connecting all cell classes in the cochlea
cells, which are defined by interconnecting gap junctions. The first system, the epithelial cell …

Connexins and gap junctions in the inner ear – it's not just about K+ recycling

DJ Jagger, A Forge - Cell and tissue research, 2015 - Springer
… and metabolic homeostasis in the inner ear. Recent studies have highlighted involvement of
… In the cochlea, gap junctions are present between the supporting cells of the organ of Corti (…

[HTML][HTML] Cochlear homeostasis and its role in genetic deafness

Z Jin, I Uhlen, K Wei-Jia, D Mao-Li - Journal of Otology, 2009 - Elsevier
gap junction networks in the cochlea, … gap junction networks are participating in cochlear
K + recirculation pathway by providing intercellular transport routes [40] . Through gap junction

Recent insights into gap junction biogenesis in the cochlea

J Defourny, M Thiry - Developmental Dynamics, 2023 - Wiley Online Library
… Cx26 and Cx30 gap junction proteins are believed to promote the rapid removal of K + …
maintain cochlear homeostasis. However, gap junctions may serve additional roles in the cochlea

Gap junctions and connexin expression in the inner ear

A Forge, D Becker, S Casalotti… - … 219‐Gap Junction …, 2007 - Wiley Online Library
… suggests gap junctions are important to cochlear function. Numerous large gap junctions
from the fluids to maintain homeostasis and auditory activity, with gap junctions providing an …

Ion and fluid homeostasis in the cochlea

P Wangemann, DC Marcus - Understanding the cochlea, 2017 - Springer
… The basal cells form a syncytium via a high density of gap junctions with fibrocytes and
the … The marginal cells are joined to each other by tight junctions but have no gap junction

Ca2+ homeostasis defects and hereditary hearing loss

F Mammano - Biofactors, 2011 - Wiley Online Library
… Actually, the idea of K + recycle through cochlear gap junction channels is challenged by
the identification of Cx26 recessive deafness mutants, for example, Cx26V84L [46], which …

Gap junction-mediated intercellular biochemical coupling in cochlear supporting cells is required for normal cochlear functions

Y Zhang, W Tang, S Ahmad, JA Sipp… - Proceedings of the …, 2005 - National Acad Sciences
cochlear cultures in which supporting cells were confirmed to be coupled by GJs, we
demonstrated that intercellular biochemical coupling in the cochlea… cellular homeostatic processes …