… Here, we examine the role of gap junctions in heart disease, focusing in particular on the …
to gap junction organization and connexin expression referred to as ‘gap junction remodelling’. …

… These specialized membrane intercellular junctions provide … Changes in the expression and
the function of connexins are … gap junctions and the expression and function of connexins in …

… communication, full phosphorylation of connexin-43, and expression in cell surface gap
junctions. These findings suggest a relation between the ability of cells to fully phosphorylate con…

… connexins after expression in the HeLa model cell-line, (2) a detailed three-dimensional view
of entire gap junctions … different connexin isotypes distribute within gap junction plaques. …

… of gap junctions and expression of connexins accompany … of gap junction organization
and connexin expression may be … of remodelling of gap junctions and connexin expression in …

… gap junction physiology, regulation of gap junction activity is complex. The structure of the
various connexins is … and activity of channels present in gap junctional plaques. The number of …

… (2004)), gap junction channels between glial cells, as in other tissues, form aggregates at
cell contacts, called gap junction plaques (Fig. 5.1 a–c). The tight packing of the gap junction …

… of coexpression of multiple connexins by a normal … connexins can be colocalized at the
same gap junction (8). In contrast, there is as yet no precedent evidence that different connexins …

… connexin Cx37, Cx40, Cx43, and Cx45. Each of these connexins can form functional gap
junctions … However, many cells coexpress more than one connexin, suggesting that they might …

… expressed, as a prelude to a detailed electrophysiological characterization. In localizing
connexins by … , as this is the principal connexin reported in other interstitial cell gap junctions [9]. …