[HTML][HTML] Human articular chondrocytes express multiple gap junction proteins: differential expression of connexins in normal and osteoarthritic cartilage
MD Mayan, P Carpintero-Fernandez… - The American journal of …, 2013 - Elsevier
… junction proteins called connexins (Cxs). We show that human chondrocytes in tissue express
… We also find that primary chondrocytes from adults retain the capacity to form functional …
… We also find that primary chondrocytes from adults retain the capacity to form functional …
[HTML][HTML] Intercellular communication via gap junction channels between chondrocytes and bone cells
P Carpintero-Fernandez, R Gago-Fuentes… - … et Biophysica Acta (BBA …, 2018 - Elsevier
… BCs and SCs, and to determine the extent of gap junction mediated coupling, we performed
experiments on cell pairs to record junctional currents by dual whole-cell voltage clamp. Fig. …
experiments on cell pairs to record junctional currents by dual whole-cell voltage clamp. Fig. …
Articular chondrocyte network mediated by gap junctions: role in metabolic cartilage homeostasis
MD Mayan, R Gago-Fuentes… - Annals of the …, 2015 - ard.bmj.com
… methods.20 ,21 Primary human chondrocytes were placed on an inverted microscope for …
of a monolayer of primary chondrocytes obtained from human adults, as previously reported.…
of a monolayer of primary chondrocytes obtained from human adults, as previously reported.…
[HTML][HTML] … gap junctions and Cx43 expression in immortalized human chondrocyte cell line: a potential model in the study of cell communication in human chondrocytes
R Gago-Fuentes, P Carpintero-Fernandez… - Osteoarthritis and …, 2014 - Elsevier
… group have revealed that primary human chondrocytes in tissue and in … gap junction (GJ)
channels. These results challenge the existing thesis of cartilage physiology, that chondrocytes …
channels. These results challenge the existing thesis of cartilage physiology, that chondrocytes …
Chondrocytes isolated from mature articular cartilage retain the capacity to form functional gap junctions
HJ Donahue, F Guilak, MA Vander Molen… - Journal of bone and …, 1995 - academic.oup.com
… gap junctions in chondrocytes isolated from mature cartilage. These gap junctions are
composed of Cx43, a gap junction-… , chondrocytes isolated from mature cartilage express a gap …
composed of Cx43, a gap junction-… , chondrocytes isolated from mature cartilage express a gap …
Joint diseases: from connexins to gap junctions
HJ Donahue, RW Qu, DC Genetos - Nature Reviews Rheumatology, 2018 - nature.com
… Cx43 localizes to the margin of cells and is expressed in 80–100% of chondrocytes in
each zone; it forms gap junctions when a lacuna contains multiple chondrocytes 76 (Fig. 3). …
each zone; it forms gap junctions when a lacuna contains multiple chondrocytes 76 (Fig. 3). …
[HTML][HTML] Functional roles of connexins and gap junctions in osteo-chondral cellular components
A Zappalà, IR Romano, F D'Angeli… - International Journal of …, 2023 - mdpi.com
… in the mouse and human genomes [6,7]. Gap junctions consent intercellular transfer of small
… The importance of Cx43 for chondrocyte differentiation was underlined by results obtained …
… The importance of Cx43 for chondrocyte differentiation was underlined by results obtained …
[HTML][HTML] Gap junctions in skeletal development and function
JP Stains, R Civitelli - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2005 - Elsevier
… are required for the differentiation of chondrocytes, as inhibition of gap junctional communication
with 18α-glycyrrhetinic acid reduces production of proteoglycans and type II collagen. …
with 18α-glycyrrhetinic acid reduces production of proteoglycans and type II collagen. …
Connexins and pannexins in the skeleton: gap junctions, hemichannels and more
LI Plotkin, JP Stains - Cellular and molecular life sciences, 2015 - Springer
… chondrocytes. Donahue and colleagues reported the expression of Cx43 and the presence
of functional gap junction channels in chondrocytes … of Cx43, human chondrocytes express …
of functional gap junction channels in chondrocytes … of Cx43, human chondrocytes express …
TGF‐β1 promotes gap junctions formation in chondrocytes via Smad3/Smad4 signalling
Q Wang, C Zhou, X Li, L Cai, J Zou, D Zhang… - Cell …, 2019 - Wiley Online Library
… in chondrocytes needs to be … and gap junctions in chondrocytes. To investigate the effect
of TGF-β1 on cell-cell communication, changes in cell migration and proliferation, gap junction …
of TGF-β1 on cell-cell communication, changes in cell migration and proliferation, gap junction …
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