… gas diffusion MRI and the results obtained over the decade-long research. We describe a
simple technique based on measuring gas … , that quantifies lung microstructure both in terms of …

… gases has opened a door to in vivo studies of lungs with MRI. In … microstructure, ADC values
determined by standard MRI techniques substantially depend on the parameters of the MRI …

… The high diffusion coefficient of gases can be used to probe the lung's microstructure. At 760
mmHg and room temperature (20 C), the calculated rate of self-diffusion of pure Helium-3 is …

… ) gas MRI with inhaled 3 He and 129 Xe – a method for functional and microstructural imaging
… HP gas MRI now has the potential to make an impact on clinical management by enabling …

… , is a quantitative measure of the replacement of gas into the alveoli and small airways …
MRI was used to perform simultaneous and regional quantitative measurements of lung function …

… Generally, lung ventilation and microstructural information of … and diffusion-weighted
microstructural MRI, respectively), and … diffusion-weighted microstructural MRI with both gases17, …

… gas MRI (HP MRI) has demonstrated the ability to detect changes in ventilation, perfusion,
and lung microstructure … The physical characteristics of HP gases and their application to MRI …

… -time ventilation and quantification of microstructure and regional function. The purpose
of … gas MRI that relate to regional function (ventilation imaging) and microstructure (diffusion …

… microstructure at the alveolar level from a fast (about 10 s) experiment based on MRI
measurements of hyperpolarized 3 He gas … , 17 and function as the major gas exchanging units of …

… functional and structural imaging of the lungs. Hyperpolarized gas diffusion-weighted (DW)
MRI provides noninvasive and quantitative assessment of microstructural acinar changes in …