… behind hyperpolarized gas diffusion MRI and the … gas apparent diffusion coefficient (ADC)
and an advanced technique, in vivo lung morphometry, that quantifies lung microstructure both …

… lung MRI with hyperpolarized gases. We show that a combination of the results of modeling
of gas diffusion in lung … information on the lung microstructure at the alveolar level. From an …

… of hyperpolarized gases has opened a door to in vivo studies of lungs with MRI. In this study
… time MRI images of these lung microgeometric parameters in healthy lungs and lungs with …

… use of this radiologic measure of lung microstructure to interstitial lung disease. The decreased
… quantitative imaging of lung ventilation and microstructure by 3 He MRI may be sensitive …

… relaxation of hyperpolarized 3 He gas MR signal in lung airspaces that relates signal
attenuation to physiological parameters characterizing lung microstructure. In combination with …

… using hyperpolarized noble gases The high diffusion coefficient of gases can be used to
probe the lung's microstructure. At 760 mmHg and room temperature (20 C), the calculated rate …

… weighted MRI and CT lung microstructure metrics in all lobar regions. … MRI were used
investigate changes in lung microstructure in cystic fibrosis and idiopathic pulmonary fibrosis. Lung …

… non-ionising structural imaging in certain lung disorders. In this invited review, … ) gas MRI
with inhaled 3 He and 129 Xe – a method for functional and microstructural imaging of the lung …

… He gas in lungs at the acinar level (over 90% of gas volume … measurements of lung
microstructure with established … and parameters characterizing the lung microstructure (12-14)…

… Thus, in our model of gas diffusion in lung, we consider airways rather than alveoli as the
elementary geometrical units. We approximate the airways as long cylinders—either smooth (…