[HTML][HTML] Epigenetics: an emerging player in gastric cancer

C Kang, JJ Song, J Lee, MY Kim - World journal of …, 2014 - ncbi.nlm.nih.gov
… identified several miRNAs as frequent targets of DNA methylation in gastric cancer (Table ​1).
… MGMT (O-6-methylguanine-DNA methyltransferase) has also been frequently found to be …

[HTML][HTML] DNA methylation in the Exon 1 region and complex regulation of Twist1 expression in gastric cancer cells

A Sakamoto, Y Akiyama, S Shimada, WG Zhu… - PLoS …, 2015 - journals.plos.org
… observed in various cancers including gastric cancer (GC). Although DNA methylation of the
… Twist1 has been frequently detected in primary cancers including of gastric cancer (GC) [11–…

[HTML][HTML] RNA methyltransferase NSUN2 promotes gastric cancer cell proliferation by repressing p57Kip2 by an m5C-dependent manner

L Mei, C Shen, R Miao, JZ Wang, MD Cao… - Cell death & …, 2020 - nature.com
… Indeed, Wang and colleagues 22 found that NSUN2 was associated with metastatic
progression by affecting DNA hypomethylation in human breast cancer. Gao et al. also found …

Aberrant Methylation and Silencing of the BNIP3 Gene in Colorectal and Gastric Cancer

M Murai, M Toyota, H Suzuki, A Satoh, Y Sasaki… - Clinical cancer …, 2005 - AACR
cancer, we examined the expression and DNA methylation status of BNIP3 gene in a panel
of colorectal and gastric cancer … expressing BNIP3 with the methyltransferase inhibitor 5-aza-…

Multifactorial etiology of gastric cancer

J Zabaleta - Cancer Epigenetics: Methods and Protocols, 2012 - Springer
… Most DNA methylation occurs in cytosine residues in CpG dinucleotide, but it can also be
found in other DNA bases. DNA methyltransferases add methyl groups to the CpG dinucleotide…

How to stomach an epigenetic insult: the gastric cancer epigenome

N Padmanabhan, T Ushijima, P Tan - Nature reviews Gastroenterology …, 2017 - nature.com
… epigenetic findings in gastric cancer, with a particular focus on DNA methylation
alterations … (5-mC) by the DNA methyltransferase (DNMT) family of proteins 28 . The 5-mC …

Aberrant methylation in gastric cancer associated with the CpG island methylator phenotype

M Toyota, N Ahuja, H Suzuki, F Itoh, M Ohe-Toyota… - Cancer research, 1999 - AACR
DNA sequences (26). The methylation status of these nine loci was first examined for 27
gastric cancers … methylation (through a mutation in DNA-methyltransferase for example) or loss …

Helicobacter pylori induces promoter methylation of E‐cadherin via interleukin‐1β activation of nitric oxide production in gastric cancer cells

FY Huang, AOO Chan, A Rashid, DKH Wong… - Cancer, 2012 - Wiley Online Library
… between DNA methylation and inflammation. In this study, we used human gastric cancer cell
… (DNMT) activity was measured using the EpiQuik DNA methyltransferase activity assay kit (…

CpG island hypermethylation in progression of esophageal and gastric cancer

F Sato, SJ Meltzer - … Journal of the American Cancer Society, 2006 - Wiley Online Library
… hypermethylation in esophageal and gastric cancers and describe topics … of aberrantly
methylated DNA in remote specimens. … as a de novo-type of DNA methyltransferase.82 One group …

[HTML][HTML] DNA methylation downregulated mir-10b acts as a tumor suppressor in gastric cancer

Z Li, H Lei, M Luo, Y Wang, L Dong, Y Ma, C Liu… - Gastric cancer, 2015 - Springer
DNA treated in vitro with Sss I methyltransferase (New England Biolabs, Beverly, MA, USA).
The DNA of … miR-10b expression in gastric cancer was suppressed by DNA methylation, the …