Genetic aspects of gastric cancer instability

P Hudler - The Scientific World Journal, 2012 - Wiley Online Library
… reported that a combination of polymorphisms within proinflammatory genes IL-1β, IL-1RA,
TNFα, and IL-10 conferred greater risk for gastric cancer development in combination with …

Oncogenic pathway combinations predict clinical prognosis in gastric cancer

CH Ooi, T Ivanova, J Wu, M Lee, IB Tan, J Tao… - … genetics, 2009 - journals.plos.org
… pathways in gastric cancer (GC) with significant relationships to patient survival. Using gene
… in 301 primary gastric cancers, the second highest cause of global cancer mortality. We …

Gastric cancer: basic aspects

C Resende, A Thiel, JC Machado, A Ristimäki - Helicobacter, 2011 - Wiley Online Library
Gastric cancer is a complex disease that arises by the combined interaction of different … A
study of HER2 gene amplification and protein expression in gastric cancer. J Clin Pathol 2010;…

Integrative approach for differentially overexpressed genes in gastric cancer by combining large-scale gene expression profiling and network analysis

A Takeno, I Takemasa, Y Doki, M Yamasaki… - … journal of cancer, 2008 - nature.com
… biological processes such as cancer initiation and progression. This … gastric cancers using
an integrated approach combining gene expression profiling of 222 human tissues and gene

A gene expression signature of acquired chemoresistance to cisplatin and fluorouracil combination chemotherapy in gastric cancer patients

HK Kim, IJ Choi, CG Kim, HS Kim, A Oshima… - PloS one, 2011 - journals.plos.org
… were collected from gastric cancer patients. We identified a gene expression signature for
acquired chemoresistance to cisplatin and fluorouracil (CF) combination chemotherapy, by …

Polymorphisms in metabolic genes, their combination and interaction with tobacco smoke and alcohol consumption and risk of gastric cancer: a case-control study in …

S Boccia, FA Sayed-Tabatabaei, R Persiani… - BMC cancer, 2007 - Springer
gastric cancer risk of several metabolic genes SNPs contemporarily, and the effect of their
combination … One of the main source of confounding in the genetic association studies arises …

Clinical Relevance and Molecular Phenotypes in Gastric Cancer, of TP53 Mutations and Gene Expressions, in Combination With Other Gene Mutations

S Park, J Lee, YH Kim, J Park, JW Shin, S Nam - Scientific Reports, 2016 - nature.com
… Using the TCGA gastric cancer dataset from cBioPortal 31 (cbioportal.org), we obtained all
the mutation rates of genes for the two groups. Subsequently, we selected the genes of which …

Genetic pathways of two types of gastric cancer.

E Tahara - IARC scientific publications, 2004 - europepmc.org
… , cell-cycle regulators, cell adhesion molecules, DNA repair genes and genetic instability
as … combinations of these alterations differ in the two histological types of gastric cancer, …

Multiple-to-multiple relationships between microRNAs and target genes in gastric cancer

Y Hashimoto, Y Akiyama, Y Yuasa - PloS one, 2013 - journals.plos.org
genes in human GCs, which might be related to gastric carcinogenesis. In this study, we
analyzed two miRNA combinationscombinations dramatically down-regulated their target genes

Integrated analysis of cancer-related pathways affected by genetic and epigenetic alterations in gastric cancer

Y Yoda, H Takeshima, T Niwa, JG Kim, T Ando… - Gastric Cancer, 2015 - Springer
… in gastric cancers (… combination of point mutations and gene amplifications showed that 58
% of GCs (29 of the 50 GCs) had at least one genetic alteration of the 55 cancer-related genes