… molecularly targeted agents of advanced gastric cancer and review emerging targeted therapies
… The goal is that a better understanding of the molecular landscape of gastric cancer will …

… To date, targeting of HER2 overexpressing tumours has met with the most success of any
targeted agent in the treatment of gastric cancer. Trastuzumab (Herceptin ©, Genentech) is a …

… Mechanism of molecular targeted therapy in gastric cancer. Molecular targeted therapy acts
on various mechanisms of gastric cancer, such as EGFR, angiogenesis, PDGF, IGF-1R, key …

… Prognosis of gastric cancer patients is poor with a five-year survival of … gastric carcinogenesis
offers novel treatment options. This review focuses on targeted treatment in gastric cancer. …

… Targeted therapy, as a new strategy, may improve the survival of advanced gastric cancer
patients. Here, we review the clinical trials related to targeted therapies for gastric cancer, …

… This article describes the actual state of the art therapeutic options in gastric cancer. Further,
the potential role of new agents in targeted therapy of gastric cancer will be evaluated and …

… cancer targets, signaling pathways, targeting therapies, and … ), MET, or the mechanistic
target of rapamycin (mTOR) have … We introduce the current knowledge of targeting therapies …

… of life, the survival of advanced gastric cancer (AGC) patients remains poor. With the advent
of targeted therapy, many molecular targeted agents have been evaluated in clinical studies. …

… acting as a single agent in patients with advanced gastroesophageal cancers… targeted
therapies will be in use for treatment of AGC. In this review, the current status of targeted therapies …

… [33], suggesting that it may be a suitable therapeutic target for gastric cancer. Therefore,
several agents targeting c-Met, including onartuzumab (humanized mAb directed against HGFR…