Altered expression and mutation of β‐catenin gene in gastric carcinomas and cell lines
… Loss of membranous β-catenin staining was associated with … that β-catenin mutations are
common in gastric cancer cell … of β-catenin in stomach cancer, we analyzed β-catenin gene …
common in gastric cancer cell … of β-catenin in stomach cancer, we analyzed β-catenin gene …
Increased β-catenin mRNA levels and mutational alterations of the APC and β-catenin gene are present in intestinal-type gastric cancer
… cancers ( 21–… frequency of mutational changes of the APC and β -catenin genes in our
series of gastric cancers, all of these genetic changes were present only in intestinal-type gastric …
series of gastric cancers, all of these genetic changes were present only in intestinal-type gastric …
Loss of beta-catenin expression in metastatic gastric cancer
… Our data did not reveal any quantitative difference in β-catenin protein levels in gastric
cancers versus normal mucosa. In agreement with a previous report by Jawhari et al, 7 we also …
cancers versus normal mucosa. In agreement with a previous report by Jawhari et al, 7 we also …
Mutational analysis of the β-catenin gene in gastric carcinomas
Y Sasaki, I Morimoto, M Kusano, M Hosokawa, F Itoh… - Tumor biology, 2000 - karger.com
… in exon 3 in 35 carcinoma tissues available for PCR … -catenin gene are rare in human gastric
carcinomas and that accumulation of normal ß-catenin protein in a subset of gastric cancers …
carcinomas and that accumulation of normal ß-catenin protein in a subset of gastric cancers …
Different patterns of β‐catenin expression in gastric carcinomas: relationship with clinicopathological parameters and prognostic outcome
H Grabsch, S Takeno, T Noguchi, G Hommel… - …, 2001 - Wiley Online Library
… Mutational analyses of β-ct in gastric carcinomas seem to corroborate this … of the β-ct gene
in gastric cancer 37 whereas, recently, in another study of 43 gastric carcinomas, 38 β-ct gene …
in gastric cancer 37 whereas, recently, in another study of 43 gastric carcinomas, 38 β-ct gene …
[HTML][HTML] Role of the Wnt/β-catenin pathway in gastric cancer: An in-depth literature review
MA Chiurillo - World journal of experimental medicine, 2015 - ncbi.nlm.nih.gov
… Moreover, a number of recent studies confirmed CTNNB1 and APC as driver genes in gastric
cancer. The identification of specific membrane, intracellular, and extracellular components …
cancer. The identification of specific membrane, intracellular, and extracellular components …
β-Catenin Mutation Is a Frequent Cause of Wnt Pathway Activation in Gastric Cancer
WM Clements, J Wang, A Sarnaik, OJ Kim… - Cancer research, 2002 - AACR
… pure populations of tumor cells for mutations in the β-catenin gene. … Exon 3 of the β-catenin
gene encodes serine-threonine … kinase that regulate degradation of β-catenin by the ubiquitin-…
gene encodes serine-threonine … kinase that regulate degradation of β-catenin by the ubiquitin-…
Frequent somatic mutations of the β-catenin gene in intestinal-type gastric cancer
WS Park, RR Oh, JY Park, SH Lee, MS Shin, YS Kim… - Cancer research, 1999 - AACR
… We identified mutations in exon 3 of the β-catenin gene in 7 of 43 sporadic gastric cancers.
All of these mutations are missense mutations, and five mutations are in aspartic acid 32, …
All of these mutations are missense mutations, and five mutations are in aspartic acid 32, …
Alterations of E-cadherin and β-catenin in gastric cancer
C Huiping, S Kristjansdottir, JG Jonasson… - BMC cancer, 2001 - Springer
… of β-catenin gene have been found in small colorectal adenomas and intestinal type gastric
cancer [18, … Here, we performed E-cadherin and beta-catenin gene mutation and expression …
cancer [18, … Here, we performed E-cadherin and beta-catenin gene mutation and expression …
[HTML][HTML] α-Catenin expression is decreased in patients with gastric carcinoma
YN Zhou, CP Xu, Y Chen, B Han… - World journal of …, 2005 - ncbi.nlm.nih.gov
… lung carcinoma cells, which do not have the α-catenin protein… Transfection of the α-catenin
gene could restore their … in the α-catenin gene[4,36], gene deletions might be involved in …
gene could restore their … in the α-catenin gene[4,36], gene deletions might be involved in …
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