Genomic heterogeneity as a barrier to precision medicine in gastroesophageal adenocarcinoma
… not suggest common heterogeneity of ERBB2 between sites (32). … genomic heterogeneity
as a potential barrier to precision medicine by evaluating the extent of genomic heterogeneity …
as a potential barrier to precision medicine by evaluating the extent of genomic heterogeneity …
Genomic landscape and genetic heterogeneity in gastric adenocarcinoma revealed by whole-genome sequencing
… However, intratumoral genetic heterogeneity during gastric tumour … of the genomic
basis of diffuse-type GC and identify the underlying genetic heterogeneity, we perform whole-genome …
basis of diffuse-type GC and identify the underlying genetic heterogeneity, we perform whole-genome …
Genomics and targeted therapies in gastroesophageal adenocarcinoma
AK Nagaraja, O Kikuchi, AJ Bass - Cancer discovery, 2019 - AACR
… Gastroesophageal adenocarcinomas (GEA) are devastating diseases with stark global …
genomic instability and heterogeneity. We highlight the potential of genomic heterogeneity to …
genomic instability and heterogeneity. We highlight the potential of genomic heterogeneity to …
Association between spatial heterogeneity within nonmetastatic gastroesophageal adenocarcinomas and survival
J Chao, V Bedell, J Lee, MS Li, P Chu… - JAMA Network …, 2020 - jamanetwork.com
… Our spatial FISH analyses also exemplify intercellular genomic heterogeneity of
actionable oncogenes at distances of less than 1 mm and greater than 4 mm. Detection of …
actionable oncogenes at distances of less than 1 mm and greater than 4 mm. Detection of …
Heterogeneity and evolution of tumour immune microenvironment in metastatic gastroesophageal adenocarcinoma
W Wang, LF Ye, H Bao, MT Hu, M Han, HM Tang… - Gastric Cancer, 2022 - Springer
… the heterogeneous fate of lesions following treatment. A seminal case study of an ovarian
cancer … To gauge the interaction between tumour genome changes and response of the host …
cancer … To gauge the interaction between tumour genome changes and response of the host …
Toward personalized treatment for gastroesophageal adenocarcinoma (GEC): Strategies to address tumor heterogeneity—PANGEA.
DVT Catenacci, BN Polite, L Henderson, P Xu… - 2014 - ascopubs.org
… Intra-patient heterogeneity may be addressed by post-treatment biopsy. … for Gastro-Esophageal
Adenocarcinoma' for metastatic GEC, integrating medium throughput proteomic/genomic …
Adenocarcinoma' for metastatic GEC, integrating medium throughput proteomic/genomic …
Circulating tumor DNA sequencing analysis of gastroesophageal adenocarcinoma
SB Maron, LM Chase, S Lomnicki, S Kochanny… - Clinical cancer …, 2019 - AACR
… therapy populations in a heterogeneous cancer by using ctDNA-NGS. … genomic alterations
(GA) and interpatient heterogeneity, exacerbated by immense intrapatient heterogeneity—…
(GA) and interpatient heterogeneity, exacerbated by immense intrapatient heterogeneity—…
Progress and challenges in HER2-positive gastroesophageal adenocarcinoma
D Zhao, SJ Klempner, J Chao - Journal of Hematology & Oncology, 2019 - Springer
… We also highlight emerging data on the genomic and temporal heterogeneity of molecular …
in gastric cancer and emerging data providing further insight into the molecular heterogeneity …
in gastric cancer and emerging data providing further insight into the molecular heterogeneity …
[HTML][HTML] Challenges of deciphering gastric cancer heterogeneity
P Hudler - World Journal of Gastroenterology: WJG, 2015 - ncbi.nlm.nih.gov
… This review addresses the heterogeneity of sporadic gastric cancer and briefly discusses the
… A wealth of research that has been performed on the genetic susceptibility of gastric cancer …
… A wealth of research that has been performed on the genetic susceptibility of gastric cancer …
HER2 genomic heterogeneity is a frequent event in gastroesophageal adenocarcinoma and correlates with tumor morphology
… genomic heterogeneity was detected in 31.6 % of the HER2-positive cases, almost exclusively
in tubular adenocarcinoma… amplification and tubular adenocarcinomas, and absence of …
in tubular adenocarcinoma… amplification and tubular adenocarcinomas, and absence of …
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