… of gastrointestinal (GI) manifestations in hereditary transthyretin amyloid (hATTR) amyloidosis
… It is well known that in the general population, functional GI disorders are more common in …

… However, these patients met the Rome IV criteria for several functional bowel disorders, but
only 23.2% underwent additional diagnostic studies for functional assessment of the luminal …

… onset of disease to the onset of gastrointestinal dysfunction. For Swedish patients, a short
period from onset of the disease to onset of gastrointestinal disturbances was correlated with …

… and demographic characteristics of amyloid in gastrointestinal biopsies. From the Amyloid
Registry Kiel, we retrieved all cases with amyloid in biopsies of the stomach, duodenum, small …

… Common diseases that cause AA amyloid are … amyloid that arises from deposition of
transthyretin protein.14, 68 All types of amyloidosis have important effects on the gastrointestinal …

… determined that WT TTR amyloid may also cause several other disorders and conditions [12]…
model transgenic for human TTR Val30Met with amyloid deposition in the GI tract [112]. This …

… In studies involving patients with early-onset disease, GI dysfunction and OH emerged in …
with Val30Met mutations reported that the GI symptoms constituted the initial symptom in nearly …

… However, the severity of cardiac or digestive disorders must be the subject of multidisciplinary
evaluation before treatment introduction. In all cases, close monitoring of tolerance and …

… First, GI manifestations are associated with significant GI amyloid fibril deposition. The …
amyloid deposition in the GI tract represents the gold standard for the diagnosis of GI amyloidosis. …

… Autonomic dysfunction, caused by amyloid affecting the Auerbach's and Meissner's plexuses
and the autonomic ganglia, induces rapid transit. Bile acid malabsorption may occur from …