… The pathogenesis of the gastrointestinal disturbances is probabaly similar in all neuropathic
forms of TTR amyloidosis. The mechanism leading to gastrointestinal dysfunction in FAP is …

… amyloidosis on the peripheral nervous, hepatic, and GI systems. The Working Group comprised
amyloidosis … with GI disorders including gastroesophageal reflux disease, inflammatory …

… , orthostatic hypotension, vitreous opacities and bowel dysfunction (Table 2). Periorbital
bruising and macroglossia can be present, but they are far more common in AL amyloidosis. …

… Relatively few patients with wild-type TTR amyloidosis reported gastrointestinal symptoms
(… Because TTR amyloidosis is a rare disorder, patient accrual is likely to be slow. Furthermore, …

… It is significant that in addition to symptoms of cardiomyopathy, other systemic phenotypes
such as polyneuropathy and gastrointestinal disorders may be present. Because of the age-…

… Gastrointestinal dysfunction due to autonomous neuropathy is a complication described in
various diseases … with gastrointestinal motility dysfunction than with amyloid deposits in the …

… reduction of TTR load in all GI tract organs analyzed. In stomach, the major organ of TTR
deposition … However, adverse side effects such as heart, liver or gastrointestinal dysfunction are …

… bowel pseudo-obstruction, as it can cause further complications without any significant benefit.
In the rare cases of only localized GI amyloidosis … Systemic AA amyloidosis is a disorder …

… Gastrointestinal symptoms Familial amyloidosis is a group of autosomal dominant
diseases that cause deposition of a homologous protein, amyloid, in the extracellular space of …

… amyloidosis. A correlative study of familial amyloid polyneuropathy and ALamyloidosis. J …
its autonomic regulation in familial amyloid polyneuropathy. Am J Cardiol 56:647-652, 1985 …