… The essential aim here is to identify those receptor mechanisms that may be … HT receptor
agonists and antagonists to modify GI motor function. 5-HT receptor types in the gastrointestinal …

… Drugs which are prescribed to increase gastrointestinal (GI) … receptor agonist and dopamine
D 2 receptor antagonist metoclopramide, the peripherally-restricted D 2 receptor antagonist …

… of 5-HT 4 receptors in regulating gastrointestinal motor and sensory … receptor antagonist.
METHODS Part A compared the effects of placebo to four doses of a 5-HT 4 receptor antagonist …

… the effect of NK1 receptor antagonism on human gastrointestinal peristalsis. We found it
therefore relevant to assess the effect of the selective NK1 receptor antagonist aprepitant on the …

… of these receptor antagonists on normal gastrointestinal motor … 5-HT receptor antagonists
on normal colonic motor activity in … 5-HT4 receptor antagonists inhibited normal colonic motor …

… Serotonin (5-hydroxytryptamine ; 5-HT) is found in the enteric nervous system where it
has been implicated in controlling gastrointestinal motor function. A number of receptor or …

… 3 (5-HT3) receptor antagonists on gastrointestinal(GI) motor activity in … GI motor activity at
all at doses up to 1 mg/kg, whereas BRL 24924 at 1.0 mg/kg iv. significantly stimulated GI motor …

… receptor types are now known to modulate the function of the gut [1, 2], and new agents are
being developed that enhance gastrointestinal motor … (stimulatory) receptors are thought to …

… The lack of hormone receptor antagonists has made it difficult to pursue this line of investigation
and to defme the physiological role of CCK in meal-induced gallbladder contraction. We …

… that SSRI effects on GI motor activities are … antagonist but not by MC4R or MC3/4R antagonists,
demonstrating the divergence in 5-HT2c receptor pathway controlling food intake and GI …