EGF receptor gene mutations are common in lung cancers from “never smokers” and are associated with sensitivity of tumors to gefitinib and erlotinib
W Pao, V Miller, M Zakowski… - Proceedings of the …, 2004 - National Acad Sciences
… , gefitinib (17, 18), we performed mutational profiling of exons 18-24 of EGFR in tumors from
10 patients … exons 18-24 in 8 and 10 patients refractory to gefitinib and erlotinib, respectively. …
10 patients … exons 18-24 in 8 and 10 patients refractory to gefitinib and erlotinib, respectively. …
[HTML][HTML] Proton pump inhibitors reduce the survival of advanced lung cancer patients with therapy of gefitinib or erlotinib
CH Lee, MC Shen, MJ Tsai, JS Chang, YB Huang… - Scientific Reports, 2022 - nature.com
… After excluding ineligible patients, the remaining 5975 patients constituted our study cohort,
including 4340 in the gefitinib cohort and 1635 in the erlotinib cohort. The TKI cohorts were …
including 4340 in the gefitinib cohort and 1635 in the erlotinib cohort. The TKI cohorts were …
Afatinib, erlotinib and gefitinib in the first-line therapy of EGFR mutation-positive lung adenocarcinoma: a review
J Koehler, M Schuler - Oncology Research and Treatment, 2013 - karger.com
… first-line erlotinib or gefitinib with cytotoxic chemotherapy in patients with … patients and the
EURTAC trial in Caucasian patients clearly demonstrated the superiority of erlotinib or gefitinib …
EURTAC trial in Caucasian patients clearly demonstrated the superiority of erlotinib or gefitinib …
Effectiveness of erlotinib in advanced non-small cell lung cancer in cases of gefitinib resistance after treatment of more than 6 months
H Saito, S Murakami, T Kondo, F Oshita… - Oncology Research …, 2012 - karger.com
… gefitinib [17]. We retrospectively studied gefitinib-resistant NSCLC p atients treated with erlotinib
… disease control (DC) rates of patients who received erlotinib after failure of long SD with …
… disease control (DC) rates of patients who received erlotinib after failure of long SD with …
Erlotinib response of EGFR-mutant gefitinib-resistant non-small-cell lung cancer
JWC Chang, CL Chou, SF Huang, HM Wang, JJ Hsieh… - Lung cancer, 2007 - Elsevier
… In this current case we demonstrated the first cross-over response to erlotinib after gefitinib
failure in a patient with an activating EGFR mutation. Serial sections on the CT scan disclosed …
failure in a patient with an activating EGFR mutation. Serial sections on the CT scan disclosed …
[HTML][HTML] … II trial of dasatinib for patients with acquired resistance to treatment with the epidermal growth factor receptor tyrosine kinase inhibitors erlotinib or gefitinib
… After restarting erlotinib or gefitinib in these patients, tumors … now recommend continued
erlotinib in patients with acquired … protocol to allow patients to continue erlotinib in addition to …
erlotinib in patients with acquired … protocol to allow patients to continue erlotinib in addition to …
Gefitinib response of erlotinib-refractory lung cancer involving meninges—role of EGFR mutation
NW Choong, S Dietrich, TY Seiwert… - Nature Clinical Practice …, 2006 - nature.com
… The patient in this case … gefitinib, 8,9,10 successful treatment of leptomeningeal metastasis
has not been reported. Furthermore, in patients who have a response to gefitinib or erlotinib …
has not been reported. Furthermore, in patients who have a response to gefitinib or erlotinib …
… deletion mutations of epidermal growth factor receptor are associated with prolonged survival in non–small cell lung cancer patients treated with gefitinib or erlotinib
DM Jackman, BY Yeap, LV Sequist, N Lindeman… - Clinical Cancer …, 2006 - AACR
… The patients included in this study represent all of the patients from our institution who met
… on treatment with gefitinib or erlotinib before March 2005. Patients were identified through a …
… on treatment with gefitinib or erlotinib before March 2005. Patients were identified through a …
A phase II trial of erlotinib in patients with EGFR wild-type advanced non-small-cell lung cancer
T Kobayashi, T Koizumi, T Agatsuma, M Yasuo… - Cancer chemotherapy …, 2012 - Springer
… In a retrospective analysis comparing the effectiveness of erlotinib and gefitinib in patients
with EGFR wild-type NSCLC, there are no differences in response rate or survival rate …
with EGFR wild-type NSCLC, there are no differences in response rate or survival rate …
[HTML][HTML] Comparison of the incidence and pattern of interstitial lung disease during erlotinib and gefitinib treatment in Japanese Patients with non-small cell lung …
K Hotta, K Kiura, N Takigawa, H Yoshioka… - Journal of Thoracic …, 2010 - Elsevier
… We investigated the incidence of ILD in Japanese patients treated with gefitinib or erlotinib.
… in Japanese patients with NSCLC who were treated with gefitinib or erlotinib monotherapy in …
… in Japanese patients with NSCLC who were treated with gefitinib or erlotinib monotherapy in …