Comparison of gefitinib and erlotinib in advanced NSCLC and the effect of EGFR mutations
JY Wu, SG Wu, CH Yang, YL Chang, YC Chang… - Lung cancer, 2011 - Elsevier
… Erlotinib was prescribed more frequently than gefitinib in … EGFR, the effectiveness of gefitinib
and erlotinib, including drug … drug selection between erlotinib and gefitinib in clinical practice…
and erlotinib, including drug … drug selection between erlotinib and gefitinib in clinical practice…
Comparison of gefitinib, erlotinib and afatinib in non‐small cell lung cancer: a meta‐analysis
… Gefitinib, erlotinib and afatinib are three widely used … ) for treating advanced non-small cell
lung cancer (NSCLC) with proven … Gefitinib and erlotinib demonstrated comparable effects on …
lung cancer (NSCLC) with proven … Gefitinib and erlotinib demonstrated comparable effects on …
Gefitinib and erlotinib in metastatic non-small cell lung cancer: a meta-analysis of toxicity and efficacy of randomized clinical trials
M Burotto, EE Manasanch, J Wilkerson, T Fojo - The oncologist, 2015 - academic.oup.com
… that the accumulated evidence with erlotinib and gefitinib indicates gefitinib's activity and
safety as a cancer therapeutic for patients with NSCLC is at least as good as that of erlotinib. …
safety as a cancer therapeutic for patients with NSCLC is at least as good as that of erlotinib. …
[HTML][HTML] A phase III randomised controlled trial of erlotinib vs gefitinib in advanced non-small cell lung cancer with EGFR mutations
JJ Yang, Q Zhou, HH Yan, XC Zhang, HJ Chen… - … journal of cancer, 2017 - nature.com
… receive erlotinib (150 mg per day) or gefitinib (250 mg per day) orally until disease progression
or unacceptable toxicity. We aimed to determine whether erlotinib is superior to gefitinib …
or unacceptable toxicity. We aimed to determine whether erlotinib is superior to gefitinib …
[HTML][HTML] Gefitinib or erlotinib in the treatment of advanced non-small cell lung cancer
YY Shao, CC Lin, CH Yang - Discovery Medicine, 2010 - discoverymedicine.com
… , gefitinib and erlotinib, have changed the treatment paradigm of advanced non-small … lung
cancer (NSCLC). Many phase II or III studies have proven the efficacy of gefitinib or erlotinib …
cancer (NSCLC). Many phase II or III studies have proven the efficacy of gefitinib or erlotinib …
Cerebrospinal fluid concentration of gefitinib and erlotinib in patients with non-small cell lung cancer
… of erlotinib are higher than those of gefitinib, which supports the view that patients can achieve
longer PFS with erlotinib treatment than with gefitinib and that erlotinib can … , than gefitinib. …
longer PFS with erlotinib treatment than with gefitinib and that erlotinib can … , than gefitinib. …
Are erlotinib and gefitinib interchangeable, opposite or complementary for non-small cell lung cancer treatment? Biological, pharmacological and clinical aspects
G Bronte, C Rolfo, E Giovannetti, G Cicero… - Critical reviews in …, 2014 - Elsevier
… identified in a patient with advanced lung cancer who progressed on erlotinib maintenance
therapy, and subsequently had leptomeningeal metastases that responded to gefitinib [33]. …
therapy, and subsequently had leptomeningeal metastases that responded to gefitinib [33]. …
EGF receptor gene mutations are common in lung cancers from “never smokers” and are associated with sensitivity of tumors to gefitinib and erlotinib
W Pao, V Miller, M Zakowski… - Proceedings of the …, 2004 - National Acad Sciences
… associated with sensitivity of lung cancers to gefitinib (Iressa), kinase inhibitor. In-…
gefitinib-sensitive tumors had similar types of alterations; no mutations were found in eight gefitinib…
gefitinib-sensitive tumors had similar types of alterations; no mutations were found in eight gefitinib…
Erlotinib, gefitinib, or chemotherapy for EGFR mutation-positive lung cancer?
T Mitsudomi - The Lancet Oncology, 2011 - thelancet.com
… for use of erlotinib, as for gefitinib. By comparison with PFS for gefitinib (10.4 months in
NEJ002 and 9.2 months in WJTOG), a median PFS of 13.1 months with erlotinib in OPTIMAL is …
NEJ002 and 9.2 months in WJTOG), a median PFS of 13.1 months with erlotinib in OPTIMAL is …
[HTML][HTML] Response to gefitinib and erlotinib in Non-small cell lung cancer: a retrospective study
IF Emery, C Battelli, PL Auclair, K Carrier, DM Hayes - BMC cancer, 2009 - Springer
… our lung cancer patients to compare the benefits derived from erlotinib and gefitinib and to
… We subsequently analyzed tumor tissue from a subgroup of these patients for a pilot study to …
… We subsequently analyzed tumor tissue from a subgroup of these patients for a pilot study to …
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