Gefitinib or Erlotinib vs Chemotherapy for EGFR Mutation-Positive Lung Cancer: Individual Patient Data Meta-Analysis of Overall Survival
CK Lee, L Davies, YL Wu, T Mitsudomi… - JNCI: Journal of the …, 2017 - academic.oup.com
… This question cannot be addressed in this meta-analysis of gefitinib and erlotinib as most of
… relative PFS benefit, OS did not statistically significantly differ between gefitinib or erlotinib vs …
… relative PFS benefit, OS did not statistically significantly differ between gefitinib or erlotinib vs …
Erlotinib after gefitinib failure in relapsed non-small cell lung cancer: clinical benefit with optimal patient selection
A Hata, N Katakami, H Yoshioka, S Fujita, K Kunimasa… - Lung cancer, 2011 - Elsevier
… Iressa Survival Evaluation in Lung Cancer (ISEL) study, gefitinib failed to show a survival
benefit … Conversely, erlotinib demonstrated a survival benefit for recurrent advanced NSCLC in …
benefit … Conversely, erlotinib demonstrated a survival benefit for recurrent advanced NSCLC in …
[HTML][HTML] Use of the epidermal growth factor receptor inhibitors gefitinib and erlotinib in the treatment of non-small cell lung cancer: a systematic review
R Feld, SS Sridhar, FA Shepherd, JA Mackay… - Journal of Thoracic …, 2006 - Elsevier
… statistically significant survival benefit for erlotinib therapy as … gefitinib as second-line or
subsequent therapy; however, a statistically significant survival benefit was not found for gefitinib …
subsequent therapy; however, a statistically significant survival benefit was not found for gefitinib …
Survival benefits from afatinib compared with gefitinib and erlotinib among patients with common EGFR mutation in first‐line setting
WC Kwok, JCM Ho, TCC Tam, MSM Ip… - Thoracic …, 2022 - Wiley Online Library
… afatinib followed by osimertinib could have survival benefit for patients with EGFR mutated
… by osimertinib in terms of survival benefit over gefitinib or erlotinib, which was not reported in …
… by osimertinib in terms of survival benefit over gefitinib or erlotinib, which was not reported in …
… survival benefit from gefitinib in patients with advanced lung adenocarcinoma: a historical comparison of patients treated before and after gefitinib approval in Japan
T Takano, T Fukui, Y Ohe, K Tsuta… - Journal of Clinical …, 2008 - ascopubs.org
… Eight large-scale, randomized, phase III trials were conducted to evaluate the survival benefits
of gefitinib or erlotinib (Tarceva; OSI Pharmaceuticals Inc, Melville, NY), another EGFR-TKI…
of gefitinib or erlotinib (Tarceva; OSI Pharmaceuticals Inc, Melville, NY), another EGFR-TKI…
[HTML][HTML] Impact on disease-free survival of adjuvant erlotinib or gefitinib in patients with resected lung adenocarcinomas that harbor EGFR mutations
YY Janjigian, BJ Park, MF Zakowski, M Ladanyi… - Journal of Thoracic …, 2011 - Elsevier
… with adjuvant cisplatin chemotherapy has no survival benefit. … of a clinical trial of perioperative
gefitinib. The surgical database … erlotinib or gefitinib delivery, disease status, and survival. …
gefitinib. The surgical database … erlotinib or gefitinib delivery, disease status, and survival. …
Gefitinib or erlotinib as maintenance therapy in patients with advanced stage non-small cell lung cancer: a systematic review
X Chen, Y Liu, OD Røe, Y Qian, R Guo, L Zhu, Y Yin… - PloS one, 2013 - journals.plos.org
… The PFS benefit was consistent in all subgroups including stage, sex, ethnicity, performance
… had more pronounced PFS benefit. Overall survival benefit was observed in patients with …
… had more pronounced PFS benefit. Overall survival benefit was observed in patients with …
[HTML][HTML] Survival benefit with erlotinib maintenance therapy in patients with advanced non-small-cell lung cancer (NSCLC) according to response to first-line …
… inhibitor (EGFR TKI) erlotinib is an established option for … Treatment with erlotinib produces
significant survival benefits … These benefits are particularly important, given that survival …
significant survival benefits … These benefits are particularly important, given that survival …
[HTML][HTML] Risk of treatment-related toxicities from EGFR tyrosine kinase inhibitors: a meta-analysis of clinical trials of gefitinib, erlotinib, and afatinib in advanced EGFR …
… A systematic review of lung cancer patients’ preferences found that even small survival
benefits are sufficient to justify chemotherapy for advanced or metastatic NSCLC, 6 but patients’ …
benefits are sufficient to justify chemotherapy for advanced or metastatic NSCLC, 6 but patients’ …
Comparison of gefitinib and erlotinib in advanced NSCLC and the effect of EGFR mutations
JY Wu, SG Wu, CH Yang, YL Chang, YC Chang… - Lung cancer, 2011 - Elsevier
… Preplanned sub-group analyses showed significantly longer survival in the gefitinib group
… Among patients of Asian origin, treatment with gefitinib showed a survival advantage than …
… Among patients of Asian origin, treatment with gefitinib showed a survival advantage than …
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