… Eligible patients with indication of gefitinib treatment were prospectively enrolled in this
study. Two peripheral blood samples at baseline and before cycle 2 day 1 were collected for the …

… study provides evidence that the efficacy of two first-generation EFGR-TKIs varies. Gefitinib
… Additional prospective, large-scale, randomized control trials are necessary to confirm this …

… He also provided testimony at theJapanese court in relation to the efficacy and toxicity of
gefitinib. The other authors declare no conflict of interest. This work was supported in part by a …

… Favorable efficacy was observed in the primary lesion and metastases to the lung, liver
and brain, while there was no obvious effect on bone metastasis. The primary lesion and …

… efficacy … -analysis that summarized direct analysis between gefitinib and erlotinib showed
no difference in OS. Also, the OS in the subgroup of patients with cerebral metastasis (6 studies…

… This study aimed to compare the efficacy of chemotherapy alone and gefitinib combined with
chemotherapy in the treatment of non-small cell lung cancer (NSCLC) patients in advanced …

… five prospective cohorts, of Japanese patients, who were genotyped for EGFR mutations and
selected to receive gefitinib … Despite the incredible response rates and efficacy of gefitinib …

… Our study aimed to assess the efficacy and safety of gefitinib as a third-line re-challenge …
In the current study, we aimed to evaluate the efficacy and safety of gefitinib as third-line …

… Our study shows afatinib to have superior CNS efficacy (longer CNS-PFS and lower …
compared with gefitinib or erlotinib in patients with EGFR-mutant NSCLC. Our previous study with a …

… 1 trials, we initiated this phase 2 trial of gefitinib. We hypothesized that blocking EGFR
tyrosine kinases with gefitinib would lead both to symptomatic benefits and objective regressions …