… gefitinib revealed no survival benefit for the gefitinib-treated … that gefitinib may be particularly
effective for treating lung … EGFR mutations and that prospective clinical trials of EGFR …

… mutations. In addition, detecting T790M may be useful for predicting pretreatment resistance
to EGFR … help clarify the role of EGFR mutations in the development of EGFR-related non–…

… and gefitinib are tyrosine kinase (TK) inhibitors of epidermal growth factor receptor (EGFR)
that are effective in treating … to compare their clinical uses and the influence of EGFR mutation. …

… Our study confirms results indicating that rare EGFR mutations are important for EGFR-TKIs
treatment outcomes (21). However, further research is required to build a database of all …

… Patients with known acquired or intrinsic EGFR resistance mutations (T790M and exon …
gefitinib treatment. Table 1 depicts the benefit–risk framework for gefitinib in the EGFR mutation–…

… brain metastases during gefitinib treatment, evaluated the efficacy of gefitinib, and examined
the association between this efficacy of gefitinib in brain metastases and EGFR mutations. …

… The efficacy of gefitinib has been explored extensively in the West and in Japan. We aimed
… activity of gefitinib as well as the relationship between response and EGFR mutation in a …

… of gefitinib in NSCLC patients with uncommon EGFR mutations, we analyzed the data of 114
patients in the gefitinib … advance the treatment of NSCLC with uncommon EGFR mutations. …

… effectiveness of gefitinib in chemotherapy-naïve NSCLC patients with EGFR mutations [29],
[… not received chemotherapy prior to gefitinib treatment responded to gefitinib (CR: two cases; …

… Here we report the case of a patient with EGFR-mutant, gefitinib-responsive, advanced non–…
complete remission during treatment with gefitinib. The DNA sequence of the EGFR gene in …