EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy

JG Paez, PA Janne, JC Lee, S Tracy, H Greulich… - Science, 2004 - science.org
… in EGFR mutation frequency between gefitinib responders (5/5) … the gefitinib responders and
unselected US NSCLC patients (5/5 … The EGFR L858R mutation, previously observed in the …

Comparison of gefitinib and erlotinib in advanced NSCLC and the effect of EGFR mutations

JY Wu, SG Wu, CH Yang, YL Chang, YC Chang… - Lung cancer, 2011 - Elsevier
lung cancer (NSCLC). This study aimed to compare their clinical uses and the influence of
EGFR mutation… a large population of NSCLC patients with gefitinib and erlotinib in order to …

EGFR Mutation Conferring Primary Resistance to Gefitinib in Non–Small-Cell Lung Cancer

JY Shih, CH Gow, PC Yang - New England Journal of Medicine, 2005 - Mass Medical Soc
mutation may cause acquired resistance to gefitinib. Our patient had concomitant T790M and
L858R EGFR mutations in … resistance to gefitinib — a finding implying that a mutation in the …

[HTML][HTML] EGFR Mutation and Resistance of Non–Small-Cell Lung Cancer to Gefitinib

S Kobayashi, TJ Boggon, T Dayaram… - … England Journal of …, 2005 - Mass Medical Soc
… of a patient with EGFR-mutant, gefitinib-responsive, advanced non–small-cell lung cancer
who had a relapse after two years of complete remission during treatment with gefitinib. The …

EGFR mutations in patients with brain metastases from lung cancer: Association with the efficacy of gefitinib

S Shimato, T Mitsudomi, T Kosaka, Y Yatabe… - Neuro …, 2006 - academic.oup.com
… in which patients received gefitinib therapy for NSCLC. From … during gefitinib treatment,
evaluated the efficacy of gefitinib, … efficacy of gefitinib in brain metastases and EGFR mutations. …

[HTML][HTML] The EGFR mutation and its correlation with response of gefitinib in previously treated Chinese patients with advanced non-small-cell lung cancer

XT Zhang, LY Li, XL Mu, QC Cui, XY Chang, W Song… - Annals of oncology, 2005 - Elsevier
gefitinib as well as the relationship between response and EGFR mutation in a series of
Chinese patients … study, four patients with disease control also had EGFR gene mutation, which …

[PDF][PDF] EGFR mutations in patients with non small-cell lung cancer in Bulgaria and treatment with gefitinib

D Damyanov, K Koynov, E Naseva, S Bichev - J buon, 2015 - jbuon.com
… In our study the rate of the EGFR mutations in NSCLC patients was 9.4%. This study also
confirmed the benefits of firstand subsequent-lines of gefitinib administration in this patient

[HTML][HTML] … of the effectiveness of erlotinib, gefitinib, and afatinib for treatment of non-small cell lung cancer in patients with common and rare EGFR gene mutations

P Krawczyk, DM Kowalski, R Ramlau… - Oncology …, 2017 - spandidos-publications.com
… of gefitinib and erlotinib in second-line therapy of Asian NSCLC patients with activating EGFR
mutations (6)… and gefitinib in first-line treatment of NSCLC patients with common activating …

[HTML][HTML] Effectiveness of gefitinib against non–small-cell lung cancer with the uncommon EGFR mutations G719X and L861Q

S Watanabe, Y Minegishi, H Yoshizawa… - Journal of thoracic …, 2014 - Elsevier
gefitinib in NSCLC patients with uncommon EGFR mutations, we analyzed the data of 114
patients in the gefitinib group and 111 patientspatients who had uncommon EGFR mutations

Gefitinib or chemotherapy for non–small-cell lung cancer with mutated EGFR

M Maemondo, A Inoue, K Kobayashi… - New England journal …, 2010 - Mass Medical Soc
… of patients with mutated-EGFR non–small-cell lung cancer are … that selecting patients on
the basis of EGFR mutations rather … result in a population with a greater sensitivity to gefitinib. …