Comparison of gefitinib, erlotinib and afatinib in non‐small cell lung cancer: a meta‐analysis

Z Yang, A Hackshaw, Q Feng, X Fu… - … journal of cancer, 2017 - Wiley Online Library
… Comparative effects of gefitinib versus erlotinib on overall survival of patients with non-small
cell lung cancer. Results are presented as individual and pooled HRs with 95% CIs. A HR …

Gefitinib and erlotinib in metastatic non-small cell lung cancer: a meta-analysis of toxicity and efficacy of randomized clinical trials

M Burotto, EE Manasanch, J Wilkerson, T Fojo - The oncologist, 2015 - academic.oup.com
… with non-small cell lung cancer (NSCLC). We demonstrated that erlotinib and gefitinib have
similar … profiles, with a suggestion of better tolerability for gefitinib. The analysis suggests that …

Comparison of gefitinib and erlotinib in advanced NSCLC and the effect of EGFR mutations

JY Wu, SG Wu, CH Yang, YL Chang, YC Chang… - Lung cancer, 2011 - Elsevier
Erlotinib and gefitinib are tyrosine kinase (TK) inhibitors of epidermal growth factor receptor
(EGFR) that are effective in treating non-small cell lung cancer (NSCLC). This study aimed to …

Cerebrospinal fluid concentration of gefitinib and erlotinib in patients with non-small cell lung cancer

Y Togashi, K Masago, S Masuda, T Mizuno… - Cancer chemotherapy …, 2012 - Springer
… (250 mg daily gefitinib or 150 mg daily erlotinib) between April 2010 and March 2012 at
Kyoto University Hospital. Two of the 15 patients received gefitinib and erlotinib treatment; …

A phase III randomised controlled trial of erlotinib vs gefitinib in advanced non-small cell lung cancer with EGFR mutations

JJ Yang, Q Zhou, HH Yan, XC Zhang, HJ Chen… - … journal of cancer, 2017 - nature.com
… A phase III trial was conducted to compare the safety and efficacy of erlotinib with that of
gefitinib in advanced non-small cell lung cancer harbouring epidermal growth factor receptor …

Risk of interstitial lung disease with gefitinib and erlotinib in advanced non-small cell lung cancer: a systematic review and meta-analysis of clinical trials

L Shi, J Tang, L Tong, Z Liu - Lung Cancer, 2014 - Elsevier
Gefitinib and erlotinib are oral epidermal growth factor receptor (EGFR) tyrosine kinase
inhibitors (TKIs) widely used in advanced non-small cell lung cancer (NSCLC). Interstitial lung

Noninvasive Detection of EGFR T790M in Gefitinib or Erlotinib Resistant Non–Small Cell Lung Cancer

Y Kuang, A Rogers, BY Yeap, L Wang… - Clinical Cancer …, 2009 - AACR
… –small cell lung cancer patients that develop resistance to gefitinib or erlotinib will contain a
secondary EGFR T790M mutation. As most patients do not undergo repeated tumor biopsies …

The Impact of Initial Gefitinib or Erlotinib versus Chemotherapy on Central Nervous System Progression in Advanced Non–Small Cell Lung Cancer with EGFR …

S Heon, BY Yeap, NI Lindeman, VA Joshi… - Clinical Cancer …, 2012 - AACR
… If validated, our results suggest that gefitinib and erlotinib may have a role in the chemoprevention
of CNS metastases from NSCLC. Clin Cancer Res; 18(16); 4406–14. ©2012 AACR. …

Randomized phase II study of gefitinib versus erlotinib in patients with advanced non-small cell lung cancer who failed previous chemotherapy

ST Kim, JE Uhm, J Lee, J Sun, I Sohn, SW Kim… - Lung Cancer, 2012 - Elsevier
Gefitinib and erlotinib are potent EGFR TKIs, with antitumor activity. In this … of gefitinib and
erlotinib was evaluated as the second-line therapy for advanced non-small cell lung cancer (…

… of Central Nervous System Metastases in Patients with Advanced Non–Small Cell Lung Cancer and Somatic EGFR Mutations Treated with Gefitinib or Erlotinib

S Heon, BY Yeap, GJ Britt, DB Costa, MS Rabin… - Clinical cancer …, 2010 - AACR
… who were treated with gefitinib or erlotinib as their initial systemic therapy for advanced
NSCLC (18). Patients who were started on treatment with gefitinib or erlotinib from January 1, …