Low-dose erlotinib treatment in elderly or frail patients with EGFR mutation–positive non–small cell lung cancer: A multicenter phase 2 trial

S Miyamoto, K Azuma, H Ishii, A Bessho… - JAMA …, 2020 - jamanetwork.com
erlotinib and gefitinib are considered equivalent. However, the recommended dose of gefitinib
Although there was no difference in plasma erlotinib concentration between the cohorts (P …

Erlotinib versus vinorelbine plus cisplatin as adjuvant therapy in Chinese patients with stage IIIA EGFR mutation-positive non-small-cell lung cancer (EVAN): a …

D Yue, S Xu, Q Wang, X Li, Y Shen, H Zhao… - The Lancet …, 2018 - thelancet.com
… Several EGFR tyrosine kinase inhibitors (TKIs), including erlotinib and gefitinib, have
been approved for the treatment of patients with EGFR mutation-positive advanced NSCLC. …

Erlotinib as salvage treatment after failure to first-line gefitinib in non-small cell lung cancer

MK Wong, AI Lo, B Lam, WK Lam, MS Ip… - Cancer chemotherapy and …, 2010 - Springer
study is to evaluate the efficacy of erlotinib, another EGFR-TKI, after failed first-line use of
gefitinib… was not a pre-requisite for response to salvage erlotinib treatment in our study cohort. …

Combined Survival Analysis of Prospective Clinical Trials of Gefitinib for Non–Small Cell Lung Cancer with EGFR Mutations

S Morita, I Okamoto, K Kobayashi, K Yamazaki… - … Cancer Research, 2009 - AACR
… (gefitinib or erlotinib) studied, given that all patients in the East Asian cohorts and our
present study were treated with gefitinib … those treated with erlotinib or gefitinib. Although the …

[HTML][HTML] Comparing gefitinib and traditional chemotherapy for better survival in patients with non-small cell lung cancer: A systematic review

S Kanagalingam, ZU Haq, NV Srinivasan, AI Khan… - Cureus, 2023 - ncbi.nlm.nih.gov
cohorts [10,16]. In contrast, most such studies did observe PFS prolonging for study cohorts,
… in such clinical cases, with gefitinib/erlotinib being the baseline reference therapy for all …

Cost-effectiveness analysis of tyrosine kinase inhibitors (erlotinib vs. gefitinib vs. afatinib) in non-small-cell lung cancer

F Nurhayati, Y Anggriani, E Syahruddin… - Journal of Applied …, 2021 - japsonline.com
… The results of the study show that afatinib therapy was superior to erlotinib and gefitinib as
first-… type used was an analytic observational retrospective cohort study. The subjects of the …

Adjuvant erlotinib versus placebo in patients with stage IB-IIIA non–small-cell lung cancer (RADIANT): A randomized, double-blind, phase III trial

K Kelly, NK Altorki, WEE Eberhardt… - Journal of Clinical …, 2015 - escholarship.org
… ) had prolonged survival with erlotinib treatment.Similarly, patients with EGFR IHC-positive
or EGFR FISH-positive tumors had superior survival with gefitinib compared with placebo.…

[HTML][HTML] Apatinib plus gefitinib as first-line treatment in advanced EGFR-mutant NSCLC: the phase III ACTIVE study (CTONG1706)

H Zhao, W Yao, X Min, K Gu, G Yu, Z Zhang… - Journal of Thoracic …, 2021 - Elsevier
… first-generation EGFR TKIs (eg, gefitinib and erlotinib) is approximately 10 to 12 months.10, …
, is a superior first-line therapy according to the FLAURA study, 11 , 12 there is no standard …

[HTML][HTML] … and subsequent systemic chemotherapy agents for advanced EGFR mutant lung adenocarcinoma patients: Implications from Taiwan cancer registry cohort

SK Liang, LT Keng, CH Chang, YF Wen, MR Lee… - Frontiers in …, 2021 - frontiersin.org
gefitinib, 1,599 erlotinib, and 1,512 afatinib) as first-line therapy were included in our study
(… To the best of our knowledge, this study is the single largest cohort study to investigate the …

Feasibility and effectiveness of afatinib for poor performance status patients with EGFR-mutation-positive non-small-cell lung cancer: a retrospective cohort study

CE Wu, CF Chang, CY Huang, CT Yang, CHS Kuo… - BMC cancer, 2021 - Springer
… A large cohort study based on the Taiwan Cancer Registry, conducted in 2011–2015,
compared the efficacy of three different TKIs—gefitinib, erlotinib, and afatinin. The results showed …