… one half of the cases of acquired resistance to gefitinib or erlotinib. The incidence of T790M
in the gefitinib/erlotinib cohort in the present study was high, reaching 79%. However, this …

… further in this cohort. Thus, we conducted a randomized phase II study to investigate the …
In the FASTACT-2 (First-line Asian Sequential Tarceva and Chemotherapy Trial 2) study, …

… cohort (afatinib 40 mg plus nimotuzumab 100 mg), one patient experienced dose-limiting
toxicity (DLT) of grade 3 diarrhea and in the subsequent cohort (… to gefitinib or erlotinib. Larger …

… the post-study treatment including cytotoxic agents and erlotinib. Regarding the … study
revealed that gefitinib was less effective in individuals with a high BSA in our prospective cohort of …

… In this population-based retrospective cohort study, we … our study cohort, including 6230
(59.7%) receiving gefitinib, … ; the number of gefitinib users decreased after erlotinib and afatinib …

… Initial Study Design Seven days after discontinuing erlotinib or gefitinib therapy, patients
began … Cohort expansion to 37 patients was planned if one or more partial responses were …

… our exploratory cohorts is too small to draw statistically robust conclusions. However, the
relatively low PFS6 and lack of radiographic responses suggest that gefitinib and erlotinib have …

… We performed a nationwide cohort study of patients newly … Citation13 Besides, compared
with gefitinib, exposure to erlotinib … Citation14 Therefore, we assume that the effects of gefitinib …

… descriptive, multicentre, and observational cohort study conducted in GH in France. … cohort.
Despite their low cerebrospinal fluid penetration rate (2.5 to 13% for erlotinib, 1% for gefitinib […

… This classification was based on previous studies demonstrating that high EGFR GCN was
… with gefitinib or erlotinib.6, 20 Therefore, 50 of 107 patients (46.7%) from the PA.3 study who …