[HTML][HTML] Efficacy and safety of afatinib for EGFR-mutant non-small cell lung cancer, compared with gefitinib or erlotinib
Y Kim, SH Lee, JS Ahn, MJ Ahn, K Park… - Cancer Research and …, 2019 - ncbi.nlm.nih.gov
… of clinical use of three EGFR TKIs (afatinib, gefitinib, and erlotinib). We found that gefitinib
was more commonly used than erlotinib or afatinib in Korea, especially for elderly, which may …
was more commonly used than erlotinib or afatinib in Korea, especially for elderly, which may …
Gefitinib and erlotinib in metastatic non-small cell lung cancer: a meta-analysis of toxicity and efficacy of randomized clinical trials
M Burotto, EE Manasanch, J Wilkerson, T Fojo - The oncologist, 2015 - academic.oup.com
… We believe that the accumulated evidence with erlotinib and gefitinib indicates gefitinib's
activity and safety as a cancer therapeutic for patients with NSCLC is at least as good as that of …
activity and safety as a cancer therapeutic for patients with NSCLC is at least as good as that of …
Gefitinib provides similar effectiveness and improved safety than erlotinib for advanced non-small cell lung cancer: A meta-analysis
W Zhang, Y Wei, D Yu, J Xu, J Peng - Medicine, 2018 - journals.lww.com
… gefitinib and erlotinib are effective for advanced non-small cell lung cancer (NSCLC). This
meta-analysis compared their effectiveness and safety… antitumor effectiveness and safety of …
meta-analysis compared their effectiveness and safety… antitumor effectiveness and safety of …
Gefitinib provides similar effectiveness and improved safety than erlotinib for east Asian populations with advanced non–small cell lung cancer: a meta-analysis
W Zhang, Y Wei, D Yu, J Xu, J Peng - BMC cancer, 2018 - Springer
… anti-tumor efficacy of gefitinib and erlotinib. However, our results indirectly prove that both
gefitinib and erlotinib are more … Both median PFS (gefitinib group, 11.4 months vs. 4.9 months; …
gefitinib and erlotinib are more … Both median PFS (gefitinib group, 11.4 months vs. 4.9 months; …
Comparison of gefitinib, erlotinib and afatinib in non‐small cell lung cancer: a meta‐analysis
… No solid evidence was found that afatinib had greater efficacy than gefitinib or erlotinib in …
, or safety.8, 19 To our knowledge, that was the only randomized trial with direct comparison of …
, or safety.8, 19 To our knowledge, that was the only randomized trial with direct comparison of …
Observational study on the efficacy and safety of erlotinib in patients with non-small cell lung cancer
T Kaburagi, H Satoh, K Hayashihara… - Oncology …, 2013 - spandidos-publications.com
… To evaluate the efficacy and safety of erlotinib for non-small cell lung … (8,9), as is gefitinib, it
is also suggested to be effective in … However, studies investigating their efficacy and safety in …
is also suggested to be effective in … However, studies investigating their efficacy and safety in …
[HTML][HTML] Risk of treatment-related toxicities from EGFR tyrosine kinase inhibitors: a meta-analysis of clinical trials of gefitinib, erlotinib, and afatinib in advanced EGFR …
… gefitinib (61.7%) than with erlotinib (17.8%) or afatinib (20.1%) (p < 0.01). A risk-benefit
contour was used to assess the trade-off between efficacy … with both erlotinib and gefitinib. With …
contour was used to assess the trade-off between efficacy … with both erlotinib and gefitinib. With …
Comparison of effectiveness and adverse effects of gefitinib, erlotinib and icotinib among patients with non‑small cell lung cancer: A network meta‑analysis
Y Liu, Y Zhang, G Feng, Q Niu… - Experimental and …, 2017 - spandidos-publications.com
… gefitinib and icotinib (P<0.05). In conclusion, gefitinib, erlotinib and icotinib had similar
effectiveness … However, gefitinib resulted in a lower frequency of fatigue, and nausea and vomiting…
effectiveness … However, gefitinib resulted in a lower frequency of fatigue, and nausea and vomiting…
A phase III randomised controlled trial of erlotinib vs gefitinib in advanced non-small cell lung cancer with EGFR mutations
JJ Yang, Q Zhou, HH Yan, XC Zhang, HJ Chen… - British journal of …, 2017 - nature.com
… conducted to compare the safety and efficacy of erlotinib with that of gefitinib in advanced
non… We aimed to determine whether erlotinib is superior to gefitinib in efficacy. The primary end …
non… We aimed to determine whether erlotinib is superior to gefitinib in efficacy. The primary end …
Randomized phase II study of gefitinib versus erlotinib in patients with advanced non-small cell lung cancer who failed previous chemotherapy
… Gefitinib and erlotinib are potent EGFR TKIs, with antitumor activity. In this randomized,
single-center, non-comparative phase II trial, the efficacy and safety of gefitinib and erlotinib was …
single-center, non-comparative phase II trial, the efficacy and safety of gefitinib and erlotinib was …
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