Gefitinib or Erlotinib vs Chemotherapy for EGFR Mutation-Positive Lung Cancer: Individual Patient Data Meta-Analysis of Overall Survival

CK Lee, L Davies, YL Wu, T Mitsudomi… - JNCI: Journal of the …, 2017 - academic.oup.com
… We assumed that gefitinib and erlotinib in the experimental … in this meta-analysis of gefitinib
and erlotinib as most of the … significantly differ between gefitinib or erlotinib vs chemotherapy …

Comparison of gefitinib and erlotinib in advanced NSCLC and the effect of EGFR mutations

JY Wu, SG Wu, CH Yang, YL Chang, YC Chang… - Lung cancer, 2011 - Elsevier
… The demographic data of these 716 patients is shown in Table 1. 302 … all patients according
to different lines of gefitinib or erlotinib. The disparities of choices on gefitinib or erlotinib (…

[HTML][HTML] Comparison of gefitinib and erlotinib efficacies as third-line therapy for advanced non-small-cell lung cancer

YY Shao, WY Shau, ZZ Lin, HM Chen, R Kuo… - European Journal of …, 2013 - Elsevier
… All medical claims data in the NHI database of every patient from the start of the third-line
treatment to the end of 2009 were examined to identify the initiation of next systemic cancer …

Comparison of adverse events and efficacy between gefitinib and erlotinib in patients with non-small-cell lung cancer: a retrospective analysis

T Yoshida, K Yamada, K Azuma, A Kawahara, H Abe… - Medical oncology, 2013 - Springer
… ; our data suggest that gefitinib and erlotinib might have … patients with EGFR-wt only, as
gefitinib and erlotinib are well known to induce a marked response and long PFS in patients with …

[HTML][HTML] Risk of treatment-related toxicities from EGFR tyrosine kinase inhibitors: a meta-analysis of clinical trials of gefitinib, erlotinib, and afatinib in advanced EGFR …

PN Ding, SJ Lord, V Gebski, M Links, V Bray… - Journal of Thoracic …, 2017 - Elsevier
… However, the Japanese trial 4 and this meta-analysis reported similar risks for diarrhea with
both erlotinib and gefitinib. With more than 2500 patients from 16 randomized trials, the data

[HTML][HTML] Gefitinib or erlotinib in the treatment of advanced non-small cell lung cancer

YY Shao, CC Lin, CH Yang - Discovery Medicine, 2010 - discoverymedicine.com
patients with different clinicopathological features or at different stages. We review the published
clinical trials that used gefitinib or erlotinib in … The OS data were not yet mature. The PFS …

Gefitinib and erlotinib in metastatic non-small cell lung cancer: a meta-analysis of toxicity and efficacy of randomized clinical trials

M Burotto, EE Manasanch, J Wilkerson, T Fojo - The oncologist, 2015 - academic.oup.com
… In this paper, we reviewed published data amassed worldwide for both erlotinib and gefitinib,
together with three randomized studies published with afatinib, to compare their toxicity …

A phase III randomised controlled trial of erlotinib vs gefitinib in advanced non-small cell lung cancer with EGFR mutations

JJ Yang, Q Zhou, HH Yan, XC Zhang, HJ Chen… - British journal of …, 2017 - nature.com
… NCT01024413) comparing erlotinib with gefitinib for patients with exon 21 mutations. The …
Finally, the efficacy data for erlotinib and gefitinib indicated that a much larger sample size …

Response to gefitinib and erlotinib in Non-small cell lung cancer: a retrospective study

IF Emery, C Battelli, PL Auclair, K Carrier, DM Hayes - BMC cancer, 2009 - Springer
data from our lung cancer patients to compare the benefits derived from erlotinib and gefitinib
… We subsequently analyzed tumor tissue from a subgroup of these patients for a pilot study …

Comparison of the effectiveness of erlotinib, gefitinib, and afatinib for treatment of non‑small cell lung cancer in patients with common and rare EGFR gene mutations

P Krawczyk, DM Kowalski, R Ramlau… - Oncology …, 2017 - spandidos-publications.com
… To the best of our knowledge, this is the first study worldwide to compare the efficacy of
erlotinib, gefitinib, and afatinib in patients with rare and common EGFR mutations. …