[HTML][HTML] Response rate is associated with prolonged survival in patients with advanced non-small cell lung cancer treated with gefitinib or erlotinib

K Tsujino, T Kawaguchi, A Kubo, N Aono… - Journal of thoracic …, 2009 - Elsevier
… 30 treatment arms, including 22 arms for the gefitinib group and 8 arms for the erlotinib group.
Both RR and DCR strongly correlated with median survival time (MST; p < 0.0001 and p = …

Duration of prior gefitinib treatment predicts survival potential in patients with lung adenocarcinoma receiving subsequent erlotinib

K Asami, M Kawahara, S Atagi, T Kawaguchi, K Okishio - Lung Cancer, 2011 - Elsevier
… : We investigated survival potential in patients receiving erlotinib after failure of gefitinib, …
patients who received erlotinib after experiencing progression with gefitinib. Our primary …

Comparison of gefitinib, erlotinib and afatinib in non‐small cell lung cancer: a meta‐analysis

Z Yang, A Hackshaw, Q Feng, X Fu… - … journal of cancer, 2017 - Wiley Online Library
Gefitinib, erlotinib and afatinib are three widely used epidermal growth factor receptor tyrosine
Gefitinib and erlotinib demonstrated comparable effects on progression‐free survival (…

Gefitinib or Erlotinib vs Chemotherapy for EGFR Mutation-Positive Lung Cancer: Individual Patient Data Meta-Analysis of Overall Survival

CK Lee, L Davies, YL Wu, T Mitsudomi… - JNCI: Journal of the …, 2017 - academic.oup.com
… We assumed that gefitinib and erlotinib in the experimental … in this meta-analysis of gefitinib
and erlotinib as most of the … significantly differ between gefitinib or erlotinib vs chemotherapy …

… deletion mutations of epidermal growth factor receptor are associated with prolonged survival in non–small cell lung cancer patients treated with gefitinib or erlotinib

DM Jackman, BY Yeap, LV Sequist, N Lindeman… - Clinical Cancer …, 2006 - AACR
… of long-term exposure to gefitinib or erlotinib that … with gefitinib or erlotinib. The aim of the
study was to correlate clinical response to gefitinib or erlotinib, time to progression, and survival

[HTML][HTML] Clinical efficacy of erlotinib, a salvage treatment for non-small cell lung cancer patients following gefitinib failure

KM Cho, B Keam, TM Kim, SH Lee… - The Korean Journal of …, 2015 - ncbi.nlm.nih.gov
erlotinib following gefitinib failure, patients who showed prolonged PFS with gefitinib benefit
from erlotinib. … As a first-line treatment, gefitinib exhibits a median progression-free survival (…

[HTML][HTML] Gefitinib or erlotinib as maintenance therapy in patients with advanced stage non-small cell lung cancer: a systematic review

X Chen, Y Liu, OD Røe, Y Qian, R Guo, L Zhu, Y Yin… - PloS one, 2013 - journals.plos.org
… of pemetrexed significantly improved the overall survival (OS) in … survival (PFS) and overall
survival (OS) with maintenance … with EGFR TKIs (gefitinib and erlotinib) produces a significant …

Comparison of gefitinib and erlotinib in advanced NSCLC and the effect of EGFR mutations

JY Wu, SG Wu, CH Yang, YL Chang, YC Chang… - Lung cancer, 2011 - Elsevier
… Our study revealed the obvious disparity in drug selection between erlotinib and gefitinib in
Gefitinib and erlotinib did not lead to different overall survival in patients with mutant EGFR. …

[HTML][HTML] Use of the epidermal growth factor receptor inhibitors gefitinib and erlotinib in the treatment of non-small cell lung cancer: a systematic review

R Feld, SS Sridhar, FA Shepherd, JA Mackay… - Journal of Thoracic …, 2006 - Elsevier
Erlotinib monotherapy is an effective treatment that can prolong survival for patients with …
Although a significant survival benefit has not been demonstrated for gefitinib in a placebo-…

[HTML][HTML] Predictive factors associated with prolonged survival in patients with advanced non-small-cell lung cancer (NSCLC) treated with gefitinib

M Satouchi, S Negoro, Y Funada, Y Urata… - British journal of …, 2007 - nature.com
… Our results showing that EGFR mutation and smoking status can function as predictors of
survival benefit differ from reports on erlotinib. However, they concur with reports to date on …