[HTML][HTML] Long non-coding RNA CASC9 promotes gefitinib resistance in NSCLC by epigenetic repression of DUSP1

Z Chen, Q Chen, Z Cheng, J Gu, W Feng, T Lei… - Cell Death & …, 2020 - nature.com
… of DUSP1 increased gefitinib sensitivity by … of CASC9 in gefitinib resistance, suggesting
that the CASC9/EZH2/DUSP1 axis might be a novel target for overcoming EGFR-TKI resistance

FOXO3-induced oncogenic lncRNA CASC9 enhances gefitinib resistance of non-small-cell lung cancer through feedback loop

Z Bing, J Han, Z Zheng, N Liang - Life sciences, 2021 - Elsevier
… lncRNA CASC9 was up-regulated in the gefitinib-resistant NSCLC … Taken together, we
hypothesized that CASC9 acted as … lncRNAs, CASC9 was one of the high-expressed RNA. In the …

Transcriptome analysis of EGFR tyrosine kinase inhibitors resistance associated long noncoding RNA in non-small cell lung cancer

P Ma, M Zhang, F Nie, Z Huang, J He, W Li… - Biomedicine & …, 2017 - Elsevier
gefitinib resistant, we chose upregulated CASC9 and downregulated LINC00277 for further
study, because CASC9 … Firstly, we knockdown of CASC9 and overexpress LINC00277 in …

[HTML][HTML] LncRNA LINC00969 promotes acquired gefitinib resistance by epigenetically suppressing of NLRP3 at transcriptional and posttranscriptional levels to inhibit …

J Dai, T Qu, D Yin, Y Cui, C Zhang, E Zhang… - Cell death & …, 2023 - nature.com
… To investigate the potential role of LINC00969 in gefitinib-resistant NSCLC cells, small
interfering RNA (siRNA)-mediated knockdown was used in conjunction with plasmid-mediated …

[HTML][HTML] … DUXAP10 contributes to gefitinib resistance in NSCLC by repressing OAS2 expression: DUXAP10 contributes to gefitinib resistance by repressing OAS2

S Ren, Y Zhu, S Wang, Q Zhang, N Zhang… - Acta Biochimica et …, 2023 - ncbi.nlm.nih.gov
… Our group indicated that long noncoding RNAs play a key role in acquired gefitinib resistance
[ 19– 21] . Pseudogenes, as noncoding RNAs, are considered to play a plethora of roles at …

[HTML][HTML] A novel circ_MACF1/miR-942-5p/TGFBR2 axis regulates the functional behaviors and drug sensitivity in gefitinib-resistant non-small cell lung cancer cells

D Fan, Y Yang, W Zhang - BMC Pulmonary Medicine, 2022 - Springer
… In this paper, we studied the precise actions of circular RNA (circRNA) microtubule … gefitinib
resistance of NSCLC. Our study demonstrated an epigenetic cause of gefitinib resistance

[HTML][HTML] HMGB1-mediated autophagy promotes gefitinib resistance in human non-small cell lung cancer: HMGB1-mediated autophagy promotes gefitinib resistance

T Lei, J Huang, F Xie, J Gu, Z Cheng… - Acta biochimica et …, 2022 - ncbi.nlm.nih.gov
… drug-resistant cells and confers to gefitinib resistance in NSCLC cells via activating autophagy
process. GefitinibRNA interference-mediated knockdown of HMGB1 reduces PC9GR cell …

Lnc-ABCA12-8 confers acquired resistance to gefitinib in non-small cell lung cancer by regulating the alternative splicing of fibronectin 1 in the IIICS region

S He, J Shi, HH Zhou, Q Li, L Wu - Cancer Gene Therapy, 2022 - nature.com
… UCA1, CASC9, CCAT1, and MALAT1 have been reported to induce gefitinib resistance
through … associated with acquired resistance to gefitinib in NSCLC using RNA sequencing, and …

[HTML][HTML] LncRNA SNHG15 regulates EGFR-TKI acquired resistance in lung adenocarcinoma through sponging miR-451 to upregulate MDR-1

J Huang, B Pan, G Xia, J Zhu, C Li, J Feng - Cell death & disease, 2020 - nature.com
… with gefitinib resistance. Long non-coding RNAs are certified to modify gefitinib resistance
in … LncRNA CASC9.5 and LINC00312 have been suggested to function as oncogenes in the …

The underlying mechanism involved in gefitinib resistance and corresponding experiment validation in lung cancer

P Song, J Zhou, K Wu, W Wang… - Mediators of Inflammation, 2023 - Wiley Online Library
… in gefitinib resistance. Chen et al. noticed that the lncRNA CASC9 could affect gefitinib
resistance … GSE123066 provides the total RNA data sequenced from wild and gefitinib-resistant