… in gefitinib resistance. Chen et al. noticed that the lncRNA CASC9 could affect gefitinib
resistance … GSE123066 provides the total RNA data sequenced from wild and gefitinib-resistant …

… And it promoted gefitinib resistance in NSCLC in vitro and in vivo through functioning as
a ceRNA for miR-143 and modulating FOSL2 expression (Chen X. et al., 2020). It has been …

… RNA quantity and quality were measured by using a … For instance, lncRNA CASC9 repressed
the DUSP1 expression … -mRNAs were obtained from gefitinib-resistant NSCLC cells using …

… hairpin RNAs (shRNAs) targeting five EGF-resistance genes for … treatment resistance,
including that against gefitinib (an … with the sensitivity or resistance to the survival response of EGF…

… inhibitory effect of lncRNA CASC9 on the tumor suppressor DUSP1, thereby promoting the
… used to isolate the total RNA. First-strand cDNA was synthesized from total RNA (2 μg) by …

… By directly targeting MET, miRNAs such as miR-1-3p and miR-206 attenuate gefitinib
resistance by inactivating the Ras/Raf/MEK/ERK and PI3K/AKT/mTOR pathways [63]. In contrast, …

… RNA Extraction and Quantitative Real-Time PCR Analysis Total RNAs of lung cancer tissues
and gefitinib-resistant … the concentrations of extracted RNAs were detected by Nanodrop (…

… For example, lncRNA CASC9 promotes gefitinib … resistance in NSCLC via epigenetic
repression of dual specificity … Then, we used RNA-seq to compare the acquired resistant cells with …

… Long non-coding RNA CASC9 promotes gefitinib resistance in NSCLC by epigenetic
repression of DUSP1. Cell Death Dis 2020; 11(10): 858. http://dx.doi.org/10.1038/s41419-020-…

… The effect of candidate tumor susceptibility gene 9 (CASC9) … gefitinib (105). Ectopic expression
of DUSP1 was found to reduce NSCLC resistance to gefitinib, suggesting that the CASC9/…