Gemcitabine: progress in the treatment of pancreatic cancer

V Heinemann - Oncology, 2000 - karger.com
pancreatic cancer has a dismal prognosis with a median survival of 3–5 months in untreated
disease. Since the introduction of gemcitabine, pancreatic cancer may … -agent gemcitabine. …

Pancreatic cancer chemoresistance to gemcitabine

M Amrutkar, IP Gladhaug - Cancers, 2017 - mdpi.com
… the regulation of gemcitabine-induced cytotoxicity in pancreatic cancer has not been …
pancreatic tumors and pancreatic cancer cell lines compared with normal pancreas and pancreatic

FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer

T Conroy, F Desseigne, M Ychou… - New England journal …, 2011 - Mass Medical Soc
… with gemcitabine in our study are in line with the results of these studies, as well as the
findings in other trials of single-agent gemcitabine in patients with advanced pancreatic cancer. …

FOLFIRINOX or gemcitabine as adjuvant therapy for pancreatic cancer

T Conroy, P Hammel, M Hebbar… - … England Journal of …, 2018 - Mass Medical Soc
… among patients with metastatic pancreatic cancer, 12 we anticipated that the 3-… gemcitabine
therapy, which would correspond to a hazard ratio for cancer-related event, second cancer, …

Role of gemcitabine in cancer therapy

L Toschi, G Finocchiaro, S Bartolini, V Gioia… - Future …, 2005 - Taylor & Francis
… -agent gemcitabine with gemcitabine plus irinotecan in 342 advanced pancreatic cancer
patients. … evaluation of the prolonged infusion strategy with gemcitabine in pancreatic cancer. …

Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine

DD Von Hoff, T Ervin, FP Arena… - New England journal …, 2013 - Mass Medical Soc
… activity in combination with gemcitabine in murine models of pancreatic cancer. In particular,
nab-paclitaxel improved the intratumoral concentration of gemcitabine. On the basis of …

p8 is a new target of gemcitabine in pancreatic cancer cells

V Giroux, C Malicet, M Barthet, M Gironella… - Clinical cancer …, 2006 - AACR
… pathways involved in the resistance of pancreatic cancer cells to gemcitabine, in the hope of
… human pancreatic cancer cell lines showing different degrees of resistance to gemcitabine

Phase II study of gemcitabine in patients with advanced pancreatic cancer

J Carmichael, U Fink, RC Russell, MF Spittle… - … journal of cancer, 1996 - nature.com
Gemcitabine has modest activity in pancreatic cancer, a limited positive improvement on
a … , gemcitabine warrants further investigation in combination studies in pancreatic cancer. …

Adjuvant chemotherapy with fluorouracil plus folinic acid vs gemcitabine following pancreatic cancer resection: a randomized controlled trial

…, f European Study Group for Pancreatic Cancer - Jama, 2010 - jamanetwork.com
… with resected pancreatic cancer. Gemcitabine is known to be the most effective agent in
advanced disease as well as an effective agent in patients with resected pancreatic cancer. …

Pancreatic cancer hENT1 expression and survival from gemcitabine in patients from the ESPAC-3 trial

, … Study Group for Pancreatic Cancer - … the National Cancer …, 2014 - academic.oup.com
… Human equilibrative nucleoside transporter 1 (hENT1) levels in pancreatic adenocarcinoma
may predict survival in patients who receive adjuvant gemcitabine after resection. …