We present an overview of clinical trials involving gene editing using clustered interspaced
short palindromic repeats (CRISPR)-CRISPR-associated protein 9 (Cas9), transcription …

… This assessment was conducted post genome editing treatment (before cell administration
to animals or human subjects) and then blood samples were collected and evaluated at …

… The CRISPR/Cas9 system with its myriad of applications has created an entirely new approach
to the study and treatment of diseases with aberrant epigenetic mechanisms. The clinical …

… is thus set to become a potential game changer in gene therapy. In the HIV clinical trial 1
, T cells harvested from HIV-infected people were treated with an adenoviral vector that …

… of disease process and their treatment in near future. Undoubtedly this field is
revolutionizing in current era and may open new vistas in the treatment of fatal genetic disease. …

… In this review, we will first discuss the state of gene editing technologies and their use as
treatments for human disease with a specific focus on CRISPR-based therapies that are …

… genome editing using ZFNs and TALENs has already reached clinical trials, the pace at
which genome editing … using genome editing to understand, treat, and cure genetic diseases. …

… gene-editing studies have found their way into the clinic, we are still waiting for clinical proof
that gene editing is actually able to treat … -up of the first clinical gene-editing trials in CD34 + …

… Prime editing further expands the scope and capabilities of genome editing. A number of
additional studies may further advance base-editing treatments for progeria towards clinical …

… study will likely have wider-reaching clinical applications. … and public debate are needed as
gene editing gears up for the clinic. … “We don’t want to be developing CRISPR treatments that …