Gene-expression signatures in breast cancer

C Sotiriou, L Pusztai - New England Journal of Medicine, 2009 - Mass Medical Soc
… In this review, we summarize the results of gene-expression studies that hold … Breast
Cancer Four main molecular classes of breast cancer have been distinguished by gene-expression

Gene expression profiling predicts clinical outcome of breast cancer

LJ Van't Veer, H Dai, MJ Van De Vijver, YD He… - nature, 2002 - nature.com
… indicate that breast cancer prognosis can already be derived from the gene expression
profile of the primary tumour. Recent consensus conferences on treatment of breast cancer in …

[HTML][HTML] Gene expression profiling in breast cancer: a clinical perspective

G Arpino, D Generali, A Sapino, L Del Matro… - The Breast, 2013 - Elsevier
… The aim of gene-expression profiling technology is to provide a better prediction of clinical …
by cancer cells remains a challenge. In this paper, we review the gene expression signatures …

Gene expression profiling in breast cancer: classification, prognostication, and prediction

JS Reis-Filho, L Pusztai - The Lancet, 2011 - thelancet.com
gene expression profiling has had a major effect on our understanding of breast cancer. …
and practical contribution of gene expression profiling in breast cancer, with special emphasis …

Gene expression profiles of human breast cancer progression

XJ Ma, R Salunga, JT Tuggle… - Proceedings of the …, 2003 - National Acad Sciences
… changes that are associated with the various stages of breast cancer progression. Contrary
… unique gene expression signatures, we find that the three distinct stages of breast cancer are …

Predicting features of breast cancer with gene expression patterns

X Lu, X Lu, ZC Wang, JD Iglehart, X Zhang… - Breast cancer research …, 2008 - Springer
gene expression arrays hold an enormous amount of biological information. We sought to
determine if global gene expression in primary breast cancers … built from gene expression data …

Gene expression predictors of breast cancer outcomes

E Huang, SH Cheng, H Dressman, J Pittman, MH Tsou… - The Lancet, 2003 - thelancet.com
gene expression related to breast cancer recurrence (though not nodal metastasis) that
generates a 70-gene … We have been unable to identify any more than 17 of these 70 genes on …

Gene-expression profiles in hereditary breast cancer

I Hedenfalk, D Duggan, Y Chen… - … England Journal of …, 2001 - Mass Medical Soc
cancers are often characteristic of the mutant gene. We hypothesized that the genes expressed
… us to identify cases of hereditary breast cancer on the basis of gene-expression profiles. …

[PDF][PDF] Gene expression profiling of breast cancer: a new tumor marker

LJ van't Veer, S Paik, DF Hayes - Journal of clinical oncology, 2005 - stati34521.narod.ru
gene expression signatures were identified when normal breast tissue was compared with
breast cancer … (or ‘‘clusters’’) based solely on gene expression patterns, without regard to any …

A gene-expression signature as a predictor of survival in breast cancer

MJ Van De Vijver, YD He, LJ Van't Veer… - … England Journal of …, 2002 - Mass Medical Soc
gene-expression signatures and to substantiate that the gene-expression profile of breast
cancer … studied a cohort of 295 young patients with breast cancer, some of whom were lymph-…