… at normally expressed mammalian genes from DNA hypermethylation, … DNA hypermethylation
of the CpG island and silencing to result. Our data suggest that DNA hypermethylation …

… true, and promoter hypermethylation now also appears to be … directly with increased gene
expression. These findings … hypermethylation and high levels of gene expression, offer …

… Accumulated in vitro data indicates that DNMTi can reverse hypermethylation DNA and
restore normal gene expression profiles in the different cancer cell lines. Promising in vitro …

… In this review, I discuss DNA hypermethylation in disease and its … of disease-associated
hypermethylation. Disease-linked … DNA hypermethylation can modulate gene expression in …

… associations between DNA methylation and gene expression. We demonstrate that DNA
hypermethylation can be associated not only with downregulation of gene expression, but also …

… genes were accompanied by differences in gene expression levels in our study. The missing
correlation with gene expression … the link between DNA methylation and gene expression is …

… within certain gene loci; however, detailed expression studies are still necessary to show
the uniform association of hypermethylation with decreased or absent gene expression. …

… In conclusion, DNMT expression and DNA hypermethylation of tumor suppressor genes in
HCCs … expression and DNA hypermethylation of specific targets. DNMT immunoreactivity and …

… ectopically activating gene expression. Lesser known are the causes of aberrant DNA
methylation. Recent studies have pointed out that intrinsic gene susceptibility to DNA methylation, …

… that HDAC inhibitors could restore expression of the silenced ER gene by reorganizing the
heterochromatin‑associated proteins without altera‑ tion in promoter DNA hypermethylation. …